A nodal point for brain-state transitions: the mesopontine tegmental anesthesia area (MPTA) in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental brain research"
DOI: 10.1007/s00221-021-06204-7
Abstract: The mesopontine tegmental anesthesia area (MPTA) was identified in rats as a singular brainstem locus at which microinjection of minute quantities of GABAergic agents rapidly and reversibly induces loss-of-consciousness and a state of general anesthesia,… read more here.
Keywords: state; mesopontine tegmental; tegmental anesthesia; area mpta ... See more keywords
Reduced Sensitivity to Anesthetic Agents upon Lesioning the Mesopontine Tegmental Anesthesia Area in Rats Depends on Anesthetic Type
Sign Up to like & getrecommendations! Published in 2019 at "Anesthesiology"
DOI: 10.1097/aln.0000000000003087
Abstract: Background: The brainstem mesopontine tegmental anesthesia area is a key node in circuitry responsible for anesthetic induction and maintenance. Microinjecting the γ-aminobutyric acid–mediated (GABAergic) anesthetic pentobarbital in this nucleus rapidly and reversibly induces general anesthesia,… read more here.
Keywords: mesopontine tegmental; anesthesia area; lesioned rats; tegmental anesthesia ... See more keywords