Kidney-targeted triptolide-encapsulated mesoscale nanoparticles for high-efficiency treatment of kidney injury.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c9bm01290g
Abstract: Bad water solubility and undesired toxicity of triptolide (TP) still restrict its clinical applications in renal diseases. In this work, well-defined, monodispersed, and uniform-sized TP-encapsulated mesoscale nanoparticles (TP-MNPs) were fabricated through a nanoprecipitation method, which… read more here.
Keywords: high efficiency; treatment; mesoscale nanoparticles; encapsulated mesoscale ... See more keywords
Mesoscale Nanoparticles: An Unexpected Means for Selective Therapeutic Targeting of Kidney Diseases!
Sign Up to like & getrecommendations! Published in 2018 at "Hypertension"
DOI: 10.1161/hypertensionaha.117.09944
Abstract: See related article, pp 87–94 Nanoparticles have attracted major interests for biomedical applications mainly as imaging contrast agents and effective drug carriers as well as the combination of both, as theranostic nanoparticles. Based on substantial… read more here.
Keywords: nanoparticles unexpected; mesoscale nanoparticles; selective therapeutic; unexpected means ... See more keywords
Mesoscale nanoparticles encapsulated with emodin for targeting antifibrosis in animal models
Sign Up to like & getrecommendations! Published in 2020 at "Open Chemistry"
DOI: 10.1515/chem-2020-0163
Abstract: Abstract The aim of this study is to explore the kidney-targeting capability of mesoscale nanoparticles (MNPs)-emodin (Em-MNPs) and its potential antifibrosis in the animal model. First, MNPs and Em-MNPs were synthesized via nanoprecipitation method, and… read more here.
Keywords: antifibrosis animal; mesoscale nanoparticles; mnps; kidney ... See more keywords