Exploring High Aspect Ratio Gold Nanotubes as Cytosolic Agents: Structural Engineering and Uptake into Mesothelioma Cells.
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DOI: 10.1002/smll.202003793
Abstract: The generation of effective and safe nanoagents for biological applications requires their physicochemical characteristics to be tunable, and their cellular interactions to be well characterized. Here, the controlled synthesis is developed for preparing high-aspect ratio… read more here.
Keywords: mesothelioma cells; ratio gold; aspect ratio; gold nanotubes ... See more keywords
BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state
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DOI: 10.1371/journal.pone.0203003
Abstract: Malignant pleural mesothelioma is an aggressive cancer with poor prognosis. Here we have investigated in vitro efficacy of BAMLET and BLAGLET complexes (anti-cancer complexes consisting of oleic acid and bovine α-lactalbumin or β-lactoglobulin respectively) in… read more here.
Keywords: mesothelioma cells; mesothelioma; bamlet blaglet; oleic acid ... See more keywords
Activation of JNK and IRE1 is critically involved in tanshinone I-induced p62 dependent autophagy in malignant pleural mesothelioma cells: implication of p62 UBA domain
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DOI: 10.18632/oncotarget.15336
Abstract: The aim of present study is to elucidate autophagic mechanism of tanshinone I (Tan I) in H28 and H2452 mesothelioma cells. Herein, Tan I exerted cytotoxicity with autophagic features of autophagy protein 5 (ATG5)/ microtubule-associated… read more here.
Keywords: mesothelioma cells; h28 cells; jnk; p62 ... See more keywords
Insulin-Like Growth Factor 2 mRNA Binding Protein 3 Promotes Cell Proliferation of Malignant Mesothelioma Cells by Downregulating p27Kip1
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.795467
Abstract: Malignant mesothelioma is a tumor with a poor prognosis, mainly caused by asbestos exposure and with no adequate treatment yet. To develop future therapeutic targets, we analyzed the microarray dataset GSE 29370 of malignant mesothelioma… read more here.
Keywords: mesothelioma cells; mesothelioma; malignant mesothelioma; cell proliferation ... See more keywords
Quinacrine Has Preferential Anticancer Effects on Mesothelioma Cells With Inactivating NF2 Mutations
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DOI: 10.3389/fphar.2021.750352
Abstract: Mesothelioma is a rare cancer with disproportionately higher death rates for shipping and mining populations. These patients have few treatment options, which can be partially attributed to limited chemotherapy responses for tumors. We initially hypothesized… read more here.
Keywords: nf2 mutations; mesothelioma cells; preferential anticancer; inactivating nf2 ... See more keywords
Concurrent induction of apoptosis and necroptosis in apigenin‑treated malignant mesothelioma cells: Reversal of Warburg effect through Akt inhibition and p53 upregulation
Sign Up to like & getrecommendations! Published in 2023 at "Oncology Reports"
DOI: 10.3892/or.2023.8548
Abstract: A high dependence on aerobic glycolysis, known as the Warburg effect, is one of the metabolic features exhibited by tumor cells. Therefore, targeting glycolysis is becoming a very promising strategy for the development of anticancer… read more here.
Keywords: mesothelioma cells; apigenin; warburg effect; malignant mesothelioma ... See more keywords