Aberrant expression of NPPB through YAP1 and TAZ activation in mesothelioma with Hippo pathway gene alterations.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6056
Abstract: BACKGROUND Mesothelioma is a neoplastic disease associated with asbestos exposure. It is highly malignant and has a poor prognosis; thus, early detection is desirable. Recent whole-genome analysis has revealed that mesothelioma is characterized by a… read more here.
Keywords: hippo pathway; pathway gene; mesothelioma patients; expression ... See more keywords
The psychosocial impact of living with mesothelioma: Experiences and needs of patients and their carers regarding supportive care.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of cancer care"
DOI: 10.1111/ecc.13498
Abstract: OBJECTIVE Mesothelioma is a rare cancer with a poor prognosis caused by exposure to asbestos. Psychosocial support and care for mesothelioma patients and their carers is limited and not tailored to their specific needs. The… read more here.
Keywords: mesothelioma; mesothelioma patients; psychosocial support; care ... See more keywords
Tumor-Derived GM-CSF Promotes Granulocyte Immunosuppression in Mesothelioma Patients
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DOI: 10.1158/1078-0432.ccr-17-3757
Abstract: Purpose: The cross-talk between tumor cells, myeloid cells, and T cells can play a critical role in tumor pathogenesis and response to immunotherapies. Although the etiology of mesothelioma is well understood, the impact of mesothelioma… read more here.
Keywords: mesothelioma; mesothelioma patients; tumor cells; csf ... See more keywords
Circulating Levels of PD-L1 in Mesothelioma Patients from the NIBIT-MESO-1 Study: Correlation with Survival
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DOI: 10.3390/cancers12020361
Abstract: Targeting of the programmed cell death protein (PD)-1/programmed death-ligand 1 (PD-L1) axis has shown a significant clinical impact in several tumor types. Accordingly, our phase II NIBIT-MESO-1 study demonstrated an improved clinical efficacy in mesothelioma… read more here.
Keywords: mesothelioma patients; nibit meso; survival; meso study ... See more keywords