CD146 immunohistochemical staining for the separation of benign from malignant mesothelial proliferations
Sign Up to like & getrecommendations! Published in 2021 at "Virchows Archiv"
DOI: 10.1007/s00428-021-03077-7
Abstract: The separation of benign from malignant mesothelial cells is often a challenging problem. Some studies have suggested that immunohistochemical staining of CD146 can be used to make this distinction, but there are marked differences in… read more here.
Keywords: immunohistochemical staining; mesotheliomas; malignant mesothelial; separation benign ... See more keywords
Usefulness of p16/CDKN2A fluorescence in situ hybridization and BAP1 immunohistochemistry for the diagnosis of biphasic mesothelioma.
Sign Up to like & getrecommendations! Published in 2017 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2016.10.010
Abstract: Malignant mesothelioma is a highly aggressive neoplasm, and the histologic subtype is one of the most reliable prognostic factors. Some biphasic mesotheliomas are difficult to distinguish from epithelioid mesotheliomas with atypical fibrous stroma. The aim… read more here.
Keywords: mesothelioma; mesotheliomas; biphasic mesothelioma; p16 cdkn2a ... See more keywords
The potential utility of GATA3 for diagnosis of malignant pleural mesotheliomas.
Sign Up to like & getrecommendations! Published in 2020 at "Human pathology"
DOI: 10.1016/j.humpath.2020.08.005
Abstract: Malignant pleural mesothelioma is associated with asbestos exposure and poor outcomes. The usefulness of immunohistochemistry for diagnosis of sarcomatoid mesothelioma, especially the desmoplastic type, is limited and more effective markers are required. GATA3 has been… read more here.
Keywords: sarcomatoid mesothelioma; gata3; diagnosis; mesotheliomas ... See more keywords
Characterizing the distribution of alterations in mesothelioma and their correlation to morphology.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqad041
Abstract: OBJECTIVES Mesothelioma is a lethal disease that arises from the serosal lining of organ cavities. Several recurrent alterations have been observed in pleural and peritoneal -mesotheliomas, including in BAP1, NF2, and CDKN2A. Although specific histopathologic… read more here.
Keywords: epithelioid mesotheliomas; biphasic mesotheliomas; alteration; correlation ... See more keywords