Evaluation of Seropositivity Following BNT162b2 Messenger RNA Vaccination for SARS-CoV-2 in Patients Undergoing Treatment for Cancer
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2021.2155
Abstract: Key Points Question Do patients with cancer develop adequate antibody responses to messenger RNA SARS-CoV-2 vaccines? Findings In this cohort study that included 102 patients with cancer who were receiving active treatment and 78 healthy… read more here.
Keywords: treatment; patients cancer; cancer; sars cov ... See more keywords
Estimated Effectiveness of Postpartum Maternal Messenger RNA COVID-19 Vaccination Against Delta and Omicron SARS-CoV-2 Infection and Hospitalization in Infants Younger Than 6 Months
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2022.6134
Abstract: This case-control study estimates the effectiveness of maternal postpartum messenger RNA (mRNA) COVID-19 vaccination against Delta and Omicron SARS-CoV-2 infection and hospitalization in infants younger than 6 months. read more here.
Keywords: messenger rna; vaccination delta; omicron sars; covid vaccination ... See more keywords
Messenger RNA vaccine advances provide treatment possibilities for cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34068
Abstract: C may have put messenger RNA (mRNA) vaccine technology on the map, but investigation into the safety and efficacy of this vaccine approach first began in oncology, where it has long been studied for therapeutic… read more here.
Keywords: messenger rna; mrna vaccines; cancer messenger; treatment ... See more keywords
Nanoparticle-Based Follistatin Messenger RNA Therapy for Reprogramming Metastatic Ovarian Cancer and Ameliorating Cancer-Associated Cachexia.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202204436
Abstract: This study presents the first messenger RNA (mRNA) therapy for metastatic ovarian cancer and cachexia-induced muscle wasting based on lipid nanoparticles that deliver follistatin (FST) mRNA predominantly to cancer clusters following intraperitoneal administration. The secreted… read more here.
Keywords: messenger rna; ovarian cancer; therapy; associated cachexia ... See more keywords
Messenger RNA-Based Vaccines Against Infectious Diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2020_202
Abstract: In vitro-transcribed, messenger RNA-based infectious disease vaccines have the potential to successfully address many of the weaknesses of traditional vaccine platforms, such as the lack of potency and/or durability of vaccine protection, time-consuming, and expensive… read more here.
Keywords: based vaccines; infectious diseases; rna based; vaccine ... See more keywords
Messenger RNA Sequencing of Rare Cell Populations in the Lung and Lung-Draining Lymph Nodes.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6786-5_14
Abstract: Next-generation sequencing (NGS) techniques provide unique prospects for in-depth transcriptome analyses. Nevertheless, the emerging and still growing knowledge about the large diversity and heterogeneity of cells that participate in immunological responses in a tissue- and… read more here.
Keywords: populations lung; cell populations; transcriptome analyses; cell ... See more keywords
Nanoparticle-Mediated Cytoplasmic Delivery of Messenger RNA Vaccines: Challenges and Future Perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical Research"
DOI: 10.1007/s11095-021-03015-x
Abstract: The COVID-19 pandemic has left scientists and clinicians no choice but a race to find solutions to save lives while controlling the rapid spreading. Messenger RNA (mRNA)-based vaccines have become the front-runners because of their… read more here.
Keywords: vaccines challenges; delivery; future perspectives; messenger rna ... See more keywords
Messenger RNA Methylation Regulates Glioblastoma Tumorigenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer cell"
DOI: 10.1016/j.ccell.2017.03.010
Abstract: Messenger RNA (mRNA) modification provides an additional layer of gene regulation in cells. In this issue of Cancer Cell, Zhang et al. report that ALKBH5, a demethylase of the mRNA modification N6-methyladenosine, regulates proliferation and self-renewal… read more here.
Keywords: rna methylation; glioblastoma tumorigenesis; messenger rna; messenger ... See more keywords
Self-assembled small messenger RNA nanospheres for efficient therapeutic apoptin expression and synergistic Gene-Chemotherapy of breast cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2021.06.061
Abstract: In this work, small self-assembled messenger RNA nanospheres (mRNA-NSs) were successfully prepared by rolling circle transcription on a constructed apoptin plasmid. The self-assembled mRNA-NSs have a uniform diameter of approximately 65 nm, good dispersity in solution,… read more here.
Keywords: mrna nss; self assembled; breast cancer; self ... See more keywords
Hypersensitivity reactions following the Moderna messenger RNA-1273 vaccine
Sign Up to like & getrecommendations! Published in 2021 at "JAAD Case Reports"
DOI: 10.1016/j.jdcr.2021.07.040
Abstract: Fig 2. Patient 2. Erythematous rectangular patch localized to the vaccination site. To the Editor: We read with great interest the case series by Sidlow et al describing the urticarial allergic dermatitis secondary to SARS-CoV-2… read more here.
Keywords: reactions following; hypersensitivity reactions; following moderna; vaccination ... See more keywords
Acute generalized exanthematous pustulosis induced by Moderna COVID-19 messenger RNA vaccine
Sign Up to like & getrecommendations! Published in 2021 at "JAAD Case Reports"
DOI: 10.1016/j.jdcr.2021.08.013
Abstract: AGEP: acute generalized exanthematous pustulosis mRNA: messenger RNA INTRODUCTION COVID-19 caused by SARS-CoV-2 is responsible for the current pandemic. The US Food and Drug Administration recently granted emergency authorization of the Pfizer BioNTech and Moderna… read more here.
Keywords: exanthematous pustulosis; generalized exanthematous; messenger rna; acute generalized ... See more keywords