About MET expression and other biomarkers in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "Virchows Archiv"
DOI: 10.1007/s00428-017-2229-5
Abstract: Letter to the Editor The study by Sterlacci et al. reported interesting data correlating MET overexpression and MET gene amplification with clinico-pathological parameters in a large cohort of patients with surgically resected non-small cell lung… read more here.
Keywords: met expression; cell lung; expression; non small ... See more keywords
Activation of the HGF/c-MET axis promotes lenvatinib resistance in hepatocellular carcinoma cells with high c-MET expression
Sign Up to like & getrecommendations! Published in 2020 at "Medical Oncology"
DOI: 10.1007/s12032-020-01350-4
Abstract: Lenvatinib is a long-awaited alternative to sorafenib for the first-line targeted therapy of patients with advanced hepatocellular carcinoma (HCC). However, resistance to lenvatinib has also become a major obstacle to improving the prognosis of HCC… read more here.
Keywords: hcc; met expression; hgf met; lenvatinib resistance ... See more keywords
MiR-23b-3p reduces the proliferation, migration and invasion of cervical cancer cell lines via the reduction of c-Met expression
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-60143-x
Abstract: Malignant transformation and progression in cancer is associated with the altered expression of multiple miRNAs, which are considered as post-transcriptional regulators of genes participating in various cellular processes. Although, it has been proposed that miR-23b-3p… read more here.
Keywords: proliferation migration; invasion; met expression; mir 23b ... See more keywords
Abstract 3815: The clinical impact of c-MET over-expression in advanced biliary tract cancers
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-3815
Abstract: Background: c-MET is a proto-oncogene that encodes the tyrosine kinase receptor for hepatocyte growth factor (HGF). Activation of HGF-c-MET signaling involves cell invasiveness and evokes metastasis through direct involvement of tumor angiogenesis. However, the value… read more here.
Keywords: overexpression; met expression; met overexpression; significant difference ... See more keywords
A Prospective Observational Study Evaluating the Correlation of c-MET Expression and EGFR Gene Mutation with Response to Erlotinib as Second-Line Treatment for Patients with Advanced/Metastatic Non-Small-Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2018 at "Oncology"
DOI: 10.1159/000486896
Abstract: Objectives: We aimed to evaluate the prevalence and predictive role of c-MET expression and EGFR mutation in the efficacy of erlotinib in non-small-cell lung cancer (NSCLC). Methods: We prospectively recruited 196 patients with stage IV… read more here.
Keywords: response; met expression; non small; expression egfr ... See more keywords
Expression of c-Met in Primary and Recurrent Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Oncology"
DOI: 10.1159/000504806
Abstract: Background:The clinical course of hepatocellular carcinoma (HCC) is complicated, because it often recurs and shows multiple lesions, some of which progress to a more malignant form, shortening the life of the patient. The hepatocyte growth… read more here.
Keywords: hepatocellular carcinoma; primary recurrent; expression met; hcc ... See more keywords
The c-MET receptor tyrosine kinase contributes to neutrophil-driven pathology in cutaneous leishmaniasis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010247
Abstract: Neutrophils are the first line of defence against invading pathogens. Although neutrophils are well-known professional killers, some pathogens including Leishmania (L.) parasites survive in neutrophils, using these cells to establish infection. Manipulation of neutrophil recruitment… read more here.
Keywords: infection; pathology; tyrosine kinase; receptor ... See more keywords
c-MET immunohistochemical expression in sporadic and inflammatory bowel disease associated lesions
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v28.i13.1338
Abstract: BACKGROUND Post-colonoscopy colorectal cancer (CRC) rates for patients with inflammatory bowel disease (IBD) are unacceptably high. During colonoscopy, an intravenous fluorescent anti-c-MET probe may improve endoscopic detection of lesions. However, c-MET expression in IBD lesions… read more here.
Keywords: ibd; inflammatory bowel; expression; crc ... See more keywords
Prognostic impact of high c-Met expression in ovarian cancer: a meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cancer"
DOI: 10.7150/jca.26071
Abstract: High c-Met expression has been observed in epithelial ovarian cancer (EOC). However, its clinicopathological impacts remain controversial. We conducted this meta-analysis to evaluate the pathologic and prognostic significance of c-Met overexpression in patients with EOC.… read more here.
Keywords: cancer; met expression; high met; meta analysis ... See more keywords