Kidney-Targeted Drug Delivery System Based on Metformin-Grafted Chitosan for Renal Fibrosis Therapy.
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DOI: 10.1021/acs.molpharmaceut.1c00827
Abstract: Our previous study demonstrated that metformin plays an anti-fibrotic role in addition to its hypoglycemic effect. Worryingly, it often requires more than 5 times the hypoglycemic dose to achieve a satisfactory anti-fibrotic effect, which greatly… read more here.
Keywords: met gfp; gfp nps; kidney; grafted chitosan ... See more keywords