LAUSR

Differential requirement of Hippo cascade during CTNNB1 or AXIN1 mutation‐driven hepatocarcinogenesis

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1 Published in 2022 at "Hepatology"

DOI: 10.1002/hep.32693

Abstract: Background and Aims: Gain‐of‐function (GOF) mutations of CTNNB1 and loss‐of‐function (LOF) mutations of AXIN1 are recurrent genetic alterations in hepatocellular carcinoma (HCC). We aim to investigate the functional contribution of Hippo/YAP/TAZ in GOF CTNNB1 or… read more here.

Keywords: hcc; yap taz; met sgaxin1; yap ... See more keywords