Obesity and Hidradenitis Suppurativa: Targeting meta-inflammation for therapeutic gain?
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and experimental dermatology"
DOI: 10.1093/ced/llad182
Abstract: Hidradenitis Suppurativa (HS) is a chronic, suppurative condition of the pilosebaceous unit. The typical HS patient is characterized as obese, smoker, manifesting nodules, abscesses and/or draining tunnels predominantly distributed in intertriginous skin. It is established… read more here.
Keywords: obesity; hidradenitis suppurativa; meta inflammation;
The effect of plant-based diets on meta-inflammation and associated cardiometabolic disorders: a review.
Sign Up to like & getrecommendations! Published in 2022 at "Nutrition reviews"
DOI: 10.1093/nutrit/nuac020
Abstract: Meta-inflammation is a chronic, low-grade state of inflammation secondary to cardiometabolic disorders related to overweight (OW), obesity (OB), consumption of poor nutritional and hypercaloric diets with excessive amounts of lipids and sugars. It can lead… read more here.
Keywords: based diets; inflammation; plant based; cardiometabolic disorders ... See more keywords
SUN-105 Females Have Reduced Meta-Inflammation in Two States of Increased Adiposity, Obesity, and Aging
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-sun-105
Abstract: Abstract Obesity is a global health epidemic, closely associated with cardiovascular diseases (CVD), hypertension, type 2 diabetes, and atherosclerosis. Obese adipose tissue is a site and source for inflammation that is strongly associated with these… read more here.
Keywords: obesity aging; adipose tissue; obesity; meta inflammation ... See more keywords
Monocyte Trafficking and Polarization Contribute to Sex Differences in Meta-Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.826320
Abstract: Obesity is associated with systemic inflammation and immune cell recruitment to metabolic tissues. Sex differences have been observed where male mice challenged with high fat diet (HFD) exhibit greater adipose tissue inflammation than females demonstrating… read more here.
Keywords: meta inflammation; monocyte; sex differences; migration ... See more keywords
Macrophages at the Crossroad of Meta-Inflammation and Inflammaging
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DOI: 10.3390/genes13112074
Abstract: Macrophages are central players in systemic inflammation associated with obesity and aging, termed meta-inflammation and inflammaging. Activities of macrophages elicited by the two chronic conditions display shared and distinct patterns mechanistically, resulting in multifaceted actions… read more here.
Keywords: inflammation; crossroad meta; inflammation inflammaging; obesity ... See more keywords
The PI3K/Akt Pathway in Meta-Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315330
Abstract: Obesity is a global epidemic representing a serious public health burden as it is a major risk factor for the development of cardiovascular disease, stroke and all-cause mortality. Chronic low-grade systemic inflammation, also known as… read more here.
Keywords: inflammation; pi3k akt; pathway meta; akt pathway ... See more keywords
Meta-Inflammation and New Anti-Diabetic Drugs: A New Chance to Knock Down Residual Cardiovascular Risk
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24108643
Abstract: Type 2 diabetes mellitus (DM) represents, with its macro and microvascular complications, one of the most critical healthcare issues for the next decades. Remarkably, in the context of regulatory approval trials, sodium-glucose cotransporter 2 inhibitors… read more here.
Keywords: new anti; anti diabetic; cardiovascular; risk ... See more keywords