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Published in 2018 at "Data Mining and Knowledge Discovery"
DOI: 10.1007/s10618-018-0581-y
Abstract: Heterogeneous information network (HIN) is a general representation of many different applications, such as social networks, scholar networks, and knowledge networks. A key development of HIN is called PathSim based on meta-path, which measures the…
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Keywords:
unsupervised meta;
similarity;
path selection;
meta path ... See more keywords
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Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbab571
Abstract: Since miRNAs can participate in the posttranscriptional regulation of gene expression, they may provide ideas for the development of new drugs or become new biomarkers for drug targets or disease diagnosis. In this work, we…
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Keywords:
meta paths;
association prediction;
based meta;
disease association ... See more keywords
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Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac184
Abstract: Predicting drug-target interactions (DTIs) is crucial at many phases of drug discovery and repositioning. Many computational methods based on heterogeneous networks (HNs) have proved their potential to predict DTIs by capturing extensive biological knowledge and…
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Keywords:
path;
meta paths;
predicting drug;
meta path ... See more keywords
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Published in 2023 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btad297
Abstract: Abstract Summary Heterogeneous knowledge graphs (KGs) have enabled the modeling of complex systems, from genetic interaction graphs and protein-protein interaction networks to networks representing drugs, diseases, proteins, and side effects. Analytical methods for KGs rely…
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Keywords:
meta paths;
similarity search;
heterogeneous knowledge;
knowledge graphs ... See more keywords
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Published in 2020 at "IEEE Access"
DOI: 10.1109/access.2020.3034214
Abstract: With the fast development of Internet, many fields have accumulated great amount of data. And plenty of them are organized in heterogeneous information network (HIN), so analyzing HIN efficiently is very necessary. Several HIN clustering…
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Keywords:
meta paths;
weight values;
heterogeneous information;
target objects ... See more keywords
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Published in 2019 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-2644-5
Abstract: BackgroundIn the field of drug repositioning, it is assumed that similar drugs may treat similar diseases, therefore many existing computational methods need to compute the similarities of drugs and diseases. However, the calculation of similarity…
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Keywords:
emp svd;
disease associations;
drug;
drug disease ... See more keywords