Hydrogen Bond-Accelerated meta-Selective C–H Borylation of Aromatic Compounds and Expression of Functional Group and Substrate Specificities
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DOI: 10.1021/acscatal.8b05005
Abstract: We found that meta-selective C–H borylation of aromatic compounds was accelerated when using urea moiety-containing bipyridine-type ligands unlike in cases involving a bipyridine-type ligand without the urea moiety. The acceleration was due to the recognition… read more here.
Keywords: aromatic compounds; borylation aromatic; selective borylation; functional group ... See more keywords
Development of Cobalt Catalysts for the meta-Selective C(sp2)-H Borylation of Fluorinated Arenes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c01162
Abstract: Cobalt precatalysts for the meta-selective borylation of fluorinated arenes are described. Initial screening and stoichiometric reactivity studies culminated in the preparation of a cobalt alkyl precatalyst supported by the sterically protected terpyridine (5,5″-Me2ArTpy = 4'-(4-N,N'-dimethylaminophenyl)-5,5″-dimethyl-2,2':6',2″-terpyridine).… read more here.
Keywords: meta selective; cobalt; borylation fluorinated; thermodynamics ... See more keywords
meta-Selective C-H Borylation of Benzamides and Pyridines by an Iridium-Lewis Acid Bifunctional Catalyst.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b03138
Abstract: We report herein the iridium-catalyzed meta-selective C-H borylation of benzamides by using a newly designed 2,2'-bipyridine (bpy) ligand bearing an alkylaluminum biphenoxide moiety. We also demonstrate the iridium-catalyzed C3-selective C-H borylation of pyridine with a… read more here.
Keywords: lewis acid; iridium; borylation benzamides; meta selective ... See more keywords
A meta-selective-C-H alkenylation of phenol-derivatives employing a traceless organosilicon template.
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DOI: 10.1039/c7cc07093d
Abstract: A traceless organosilicon template-directed meta-selective-C-H alkenylation of phenols was realized with good yields and high selectivities. The template was readily removable through F--promoted O-Si cleavage under extremely mild conditions or recyclable through a p-TSA catalyzed… read more here.
Keywords: selective alkenylation; traceless organosilicon; organosilicon template; meta selective ... See more keywords
meta-Selective C–H difluoromethylation of various arenes with a versatile ruthenium catalyst
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DOI: 10.1039/c7qo00449d
Abstract: A ruthenium-enabled meta-selective C–H difluoromethylation of arenes has been developed. Various arenes bearing pyridyl, pyrazolyl, imidazolyl, or pyrimidyl directing groups, or removable oxazoline directing groups, were tolerated in this meta-selective C–H difluoromethylation, affording the difluoromethylated… read more here.
Keywords: ruthenium; difluoromethylation various; selective difluoromethylation; various arenes ... See more keywords
Highly meta-selective halogenation of 2-phenylpyridine with a ruthenium(I) catalyst
Sign Up to like & getrecommendations! Published in 2018 at "Organic chemistry frontiers"
DOI: 10.1039/c7qo01133d
Abstract: We report a concise, versatile, and practical method for PhI(OCOCF3)2 mediated direct meta-C–H monohalogenation of 2-phenylpyridine and its derivatives via an Ru(I)-catalyzed reaction. The significant advantage of this transformation is the creation of a highly… read more here.
Keywords: selective halogenation; phenylpyridine; halogenation phenylpyridine; phenylpyridine ruthenium ... See more keywords