Morphological Evaluation of Meta-stable Oligomers of α-Synuclein with Small-Angle Neutron Scattering
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-32655-0
Abstract: Amyloidogenesis of α-synuclein (αS) is considered to be a pathological phenomenon related to Parkinson’s disease (PD). As a key component to reveal the fibrillation mechanism and toxicity, we have investigated an oligomeric species of αS… read more here.
Keywords: stable oligomers; meta stable; small angle; neutron scattering ... See more keywords
Living on the edge of instability
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Statistical Mechanics: Theory and Experiment"
DOI: 10.1088/1742-5468/ab333f
Abstract: Statistical description of stochastic dynamics in highly unstable potentials is strongly affected by properties of divergent trajectories, that quickly leave meta-stable regions of the potential landscape and never return. Using ideas from theory of Q-processes… read more here.
Keywords: meta stable; edge instability; living edge; highly unstable ... See more keywords