Joining the dots: Questions
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Nephrology"
DOI: 10.1007/s00467-021-05394-0
Abstract: A 6-year-old girl with E beta thalassemia on regular blood transfusion and iron chelation therapy was brought to the emergency room with vomiting for the previous 2 days, low grade temperature, and decreasing consciousness. On… read more here.
Keywords: therapy; joining dots; metabolic acidosis; blood ... See more keywords
Comparison of a modified Story approach to traditional evaluation of acid–base disturbances in patients with shock: a cohort study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Monitoring and Computing"
DOI: 10.1007/s10877-021-00713-0
Abstract: To compare whether the diagnostic evaluation of metabolic acidosis can be improved by using a modified Story method compared to the traditional evaluation in a population of critically ill patients with shock. This prospective cohort… read more here.
Keywords: modified story; story; metabolic acidosis; traditional evaluation ... See more keywords
Prevalence of Metabolic Acidosis Among Patients with Chronic Kidney Disease and Hyperkalemia
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DOI: 10.1007/s12325-021-01886-5
Abstract: Although hyperkalemia and metabolic acidosis often co-occur in patients with chronic kidney disease (CKD), the prevalence of metabolic acidosis among patients with CKD and hyperkalemia is understudied. Therefore, we used medical record data from the… read more here.
Keywords: acidosis; prevalence metabolic; among patients; hyperkalemia ... See more keywords
Threshold of metabolic acidosis associated with newborn cerebral palsy: medical legal implications
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2018.11.1107
Abstract: &NA; Obstetricians and gynecologists belong to 1 of the medical specialties with the highest rate of litigation claims. Among birth injury cases, those cases with cerebral palsy outcomes account for litigation settlements or judgments often… read more here.
Keywords: cerebral palsy; base; metabolic acidosis; base deficit ... See more keywords
Methanol poisoning as a new world challenge: A review
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DOI: 10.1016/j.amsu.2021.102445
Abstract: Background Methanol poisoning (MP) occurs often via ingestion, inhalation, or dermal exposure to formulations containing methanol in base. Clinical manifestations of MP include gastrointestinal symptoms, central nervous system (CNS) suppression, and decompensated metabolic acidosis occurred… read more here.
Keywords: blurred vision; methanol; methanol poisoning; clinical manifestations ... See more keywords
SGLT2 inhibitors and metformin: Dual antihyperglycemic therapy and the risk of metabolic acidosis in type 2 diabetes
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.01.002
Abstract: &NA; The prevalence of type 2 diabetes mellitus (T2D) has risen in the United States and worldwide, with an increase in global prevalence from 4.7% to 8.5% between 1980 and 2014. A variety of antidiabetic… read more here.
Keywords: acidosis; sglt2 inhibitors; risk; type diabetes ... See more keywords
Metabolic acidosis is common and associates with disease progression in children with chronic kidney disease.
Sign Up to like & getrecommendations! Published in 2017 at "Kidney international"
DOI: 10.1016/j.kint.2017.05.006
Abstract: Recent studies in adult chronic kidney disease (CKD) suggest that metabolic acidosis is associated with faster decline in estimated glomerular filtration rate (eGFR). Alkali therapies improve the course of kidney disease. Here we investigated the… read more here.
Keywords: acidosis; metabolic acidosis; kidney disease; serum bicarbonate ... See more keywords
Deletion of the proton receptor OGR1 in mouse osteoclasts impairs metabolic acidosis-induced bone resorption.
Sign Up to like & getrecommendations! Published in 2020 at "Kidney international"
DOI: 10.1016/j.kint.2020.10.023
Abstract: Metabolic acidosis induces osteoclastic bone resorption and inhibits osteoblastic bone formation. Previously we found that mice with a global deletion of the proton receptor OGR1 had increased bone density although both osteoblast and osteoclast activity… read more here.
Keywords: bone resorption; ogr1; metabolic acidosis; mice ... See more keywords
Effects of Acid on Bone.
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DOI: 10.1016/j.kint.2022.02.032
Abstract: The homeostatic regulation of a stable systemic pH is of critical importance for mammalian survival. During metabolic acidosis (a reduction in systemic pH caused by a primary decrease in serum bicarbonate concentration), as seen in… read more here.
Keywords: bone; metabolic acidosis; calcium; acid bone ... See more keywords
In silico identification of genes involved in chronic metabolic acidosis
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DOI: 10.1016/j.lfs.2017.11.014
Abstract: Aims: Chronic metabolic acidosis (CMA) refers to increased plasma acidity due to disturbed acid‐base equilibrium in human body. CMA leads to many dysfunctions including disorders of intestinal metabolism and barrier functions. The human body responds… read more here.
Keywords: genes involved; silico identification; identification genes; chronic metabolic ... See more keywords
Effects of sodium bicarbonate infusion on mortality in medical-surgical ICU patients with metabolic acidosis-A single-center propensity score matched analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Medicina intensiva"
DOI: 10.1016/j.medin.2021.04.010
Abstract: OBJECTIVE Metabolic acidosis is associated with high mortality. Despite theoretical benefits of sodium-bicarbonate (SB), current evidence remains controversial. We investigated SB-related effects on outcomes in ICU patients with metabolic acidosis. DESIGN Retrospective analysis. SETTING Academic… read more here.
Keywords: patients metabolic; group; mortality; metabolic acidosis ... See more keywords