Expanding Metabolic Capabilities Using Novel Pathway Designs: Computational Tools and Case Studies
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DOI: 10.1002/biot.201800734
Abstract: Design and selection of efficient metabolic pathways is critical for the success of metabolic engineering endeavors. Convenient pathways should not only produce the target metabolite in high yields but also are required to be thermodynamically… read more here.
Keywords: expanding metabolic; engineering; case studies; pathway ... See more keywords
High‐quality genome‐scale metabolic modelling of Pseudomonas putida highlights its broad metabolic capabilities
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DOI: 10.1111/1462-2920.14843
Abstract: Summary Genome‐scale reconstructions of metabolism are computational species‐specific knowledge bases able to compute systemic metabolic properties. We present a comprehensive and validated reconstruction of the biotechnologically relevant bacterium Pseudomonas putida KT2440 that greatly expands computable… read more here.
Keywords: metabolic capabilities; pseudomonas putida; genome scale; high quality ... See more keywords