Retuning hepatocytes improves their functional engraftment
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32513
Abstract: Orthotopic liver transplantation is the only effective cure for endstage liver disease. Unfortunately, the current need for liver transplants by far eclipses the availability of suitable grafts, resulting in the death of many waitlisted patients,… read more here.
Keywords: functional engraftment; metabolic capacity; transplantation; liver ... See more keywords
Repeated threat (without direct harm) alters metabolic capacity in select regions that drive defensive behavior
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.04.012
Abstract: To understand the behavioral consequences of intermittent anticipatory stress resulting from threats without accompanying physiological challenges, we developed a semi-naturalistic rodent housing and foraging environment that can include threats that are unpredictable in timing. Behavior… read more here.
Keywords: group; metabolic capacity; behavior; repeated threat ... See more keywords
Sucrose Metabolism in Haloarchaea: Reassessment Using Genomics, Proteomics, and Metagenomics
Sign Up to like & getrecommendations! Published in 2019 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.02935-18
Abstract: Our ability to infer the function that microorganisms perform in the environment is predicated on assumptions about metabolic capacity. When genomic or metagenomic data are used, metabolic capacity is inferred from genetic potential. Here, we… read more here.
Keywords: haloarchaea; metabolism haloarchaea; metabolic capacity; sucrose metabolism ... See more keywords
Benzalkonium Chloride, Even at Low Concentrations, Deteriorates Intracellular Metabolic Capacity in Human Conjunctival Fibroblasts
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092315
Abstract: The objective of this study was to clarify the effects of benzalkonium chloride (BAC) on two-dimensional (2D) and three-dimensional (3D) cultures of human conjunctival fibroblast (HconF) cells, which are in vitro models replicating the epithelial… read more here.
Keywords: even low; human conjunctival; benzalkonium chloride; metabolic capacity ... See more keywords
Is the CYP2D6 Genotype Associated with Antipsychotic-Induced Weight Gain?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12101728
Abstract: Antipsychotic-induced weight gain (AIWG) is a serious adverse effect. Studies have linked genetically-predicted CYP2D6 metabolic capacity to AIWG. The evidence, however, is ambiguous. We performed multiple regression analyses examining the association between genetic-predicted CYP2D6 metabolic… read more here.
Keywords: cyp2d6 metabolic; metabolic capacity; cyp2d6; weight gain ... See more keywords