Articles with "metabolic changes" as a keyword



Obesity and cancer: A mechanistic overview of metabolic changes in obesity that impact genetic instability

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Published in 2019 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.23048

Abstract: Obesity, defined as a state of positive energy balance with a body mass index exceeding 30 kg/m2 in adults and 95th percentile in children, is an increasing global concern. Approximately one‐third of the world's population… read more here.

Keywords: genetic instability; metabolic changes; cancer; obesity ... See more keywords

Metabolic profiling of listeria rhombencephalitis in small ruminants by 1H high‐resolution magic angle spinning NMR spectroscopy

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Published in 2018 at "NMR in Biomedicine"

DOI: 10.1002/nbm.4023

Abstract: Listeria rhombencephalitis is caused by infection with Listeria monocytogenes and is associated with a high mortality rate in humans and ruminants. Little is known about the metabolic changes associated with neurolisteriosis in particular and infectious… read more here.

Keywords: listeria rhombencephalitis; rhombencephalitis small; spectroscopy; metabolic changes ... See more keywords

Metabolic changes in root exudates of plants with different disease severity affect plant resistance by regulating the rhizosphere microbiome.

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Published in 2025 at "Pest management science"

DOI: 10.1002/ps.70306

Abstract: Root exudates play a critical role in plant‐microorganism interactions. However, information on the metabolic change in root exudates of plants with different disease severities of bacterial wilt is limited. Here, we investigate the differential metabolic… read more here.

Keywords: plant; exudates plants; different disease; metabolic changes ... See more keywords

Exploring the Influence of Metabolic Changes in Fibrotic Lung Diseases

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Published in 2025 at "Pulmonary Circulation"

DOI: 10.1002/pul2.70163

Abstract: ABSTRACT Fibrotic lung diseases are often characterized by chronic inflammation and the progressive destruction of the vasculature, parenchyma, and airways, leading to cellular metabolic changes. As a result, these changes activate several pathological pathways, contributing… read more here.

Keywords: lung; metabolic changes; lung diseases; influence metabolic ... See more keywords
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Metabolic changes associated with differential salt tolerance in sorghum genotypes

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Published in 2020 at "Planta"

DOI: 10.1007/s00425-020-03437-8

Abstract: Accumulation of specific metabolites, mainly γ-aminobutyric acid, polyamines, and proline, was essential to homeostasis regulation and differential salt tolerance in sorghum genotypes. Salinity is severe abiotic stress that limits plant growth and development in arid… read more here.

Keywords: sorghum genotypes; metabolic changes; tolerance; tolerance sorghum ... See more keywords

Cerebral Metabolic Changes Related to Oxidative Metabolism in a Model of Bacterial Meningitis Induced by Lipopolysaccharide

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Published in 2018 at "Neurocritical Care"

DOI: 10.1007/s12028-018-0509-9

Abstract: BackgroundCerebral mitochondrial dysfunction is prominent in the pathophysiology of severe bacterial meningitis. In the present study, we hypothesize that the metabolic changes seen after intracisternal lipopolysaccharide (LPS) injection in a piglet model of meningitis is… read more here.

Keywords: meningitis; lps injection; metabolic changes; oxidative metabolism ... See more keywords

Dynamic species-specific metabolic changes in the trees exposed to chronic N+S additions at the Bear Brook Watershed in Maine, USA

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Published in 2019 at "Annals of Forest Science"

DOI: 10.1007/s13595-019-0808-0

Abstract: Key messageRed spruce (Picea rubens Sarg.) and American beech (Fagus grandifolia Ehrh.) nutritional imbalances observed during 1998–2000 in response to nitrogen additions beginning in 1989 at Bear Brook Watershed in Maine, USA, were reversed by… read more here.

Keywords: metabolic changes; watershed maine; species specific; maine usa ... See more keywords

Metabolic changes in tumor cells and tumor-associated macrophages: A mutual relationship.

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Published in 2018 at "Cancer letters"

DOI: 10.1016/j.canlet.2017.10.037

Abstract: In order to adapt to the reduced availability of nutrients and oxygen in the tumor microenvironment and the increased requirements of energy and building blocks necessary for maintaining their high proliferation rate, malignant cells undergo… read more here.

Keywords: tumor associated; metabolic changes; metabolism; tumor cells ... See more keywords
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Metabolic Changes Accompanying Spermatogonial Stem Cell Differentiation.

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Published in 2020 at "Developmental cell"

DOI: 10.1016/j.devcel.2020.01.014

Abstract: Male fertility is driven by spermatogonial stem cells (SSCs) that self-renew while also giving rise to differentiating spermatogonia. Spermatogonial transitions are accompanied by a shift in gene expression, however, whether equivalent changes in metabolism occur… read more here.

Keywords: accompanying spermatogonial; metabolic changes; spermatogonial stem; changes accompanying ... See more keywords
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Pyrogens, a polypeptide produces fever by metabolic changes in hypothalamus: Mechanisms and detections.

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Published in 2018 at "Immunology letters"

DOI: 10.1016/j.imlet.2018.10.006

Abstract: Fever is one of the cardinal symptoms of onset of an infection or inflammation and is the common clinical indicator for medical consultation in mammalian host worldwide. Simply, fever manifested with elevation of body temperature… read more here.

Keywords: polypeptide produces; pyrogens polypeptide; changes hypothalamus; metabolic changes ... See more keywords

CCCTC‐Binding Factor Translates Interleukin 2‐ and &agr;‐Ketoglutarate‐Sensitive Metabolic Changes in T Cells into Context‐Dependent Gene Programs

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Published in 2017 at "Immunity"

DOI: 10.1016/j.immuni.2017.07.015

Abstract: &NA; Despite considerable research connecting cellular metabolism with differentiation decisions, the underlying mechanisms that translate metabolite‐sensitive activities into unique gene programs are still unclear. We found that aspects of the interleukin‐2 (IL‐2)‐sensitive effector gene program… read more here.

Keywords: sensitive metabolic; gene programs; metabolic changes; agr sensitive ... See more keywords