Obesity and cancer: A mechanistic overview of metabolic changes in obesity that impact genetic instability
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23048
Abstract: Obesity, defined as a state of positive energy balance with a body mass index exceeding 30 kg/m2 in adults and 95th percentile in children, is an increasing global concern. Approximately one‐third of the world's population… read more here.
Keywords: genetic instability; metabolic changes; cancer; obesity ... See more keywords
Metabolic profiling of listeria rhombencephalitis in small ruminants by 1H high‐resolution magic angle spinning NMR spectroscopy
Sign Up to like & getrecommendations! Published in 2018 at "NMR in Biomedicine"
DOI: 10.1002/nbm.4023
Abstract: Listeria rhombencephalitis is caused by infection with Listeria monocytogenes and is associated with a high mortality rate in humans and ruminants. Little is known about the metabolic changes associated with neurolisteriosis in particular and infectious… read more here.
Keywords: listeria rhombencephalitis; rhombencephalitis small; spectroscopy; metabolic changes ... See more keywords
Metabolic changes associated with differential salt tolerance in sorghum genotypes
Sign Up to like & getrecommendations! Published in 2020 at "Planta"
DOI: 10.1007/s00425-020-03437-8
Abstract: Accumulation of specific metabolites, mainly γ-aminobutyric acid, polyamines, and proline, was essential to homeostasis regulation and differential salt tolerance in sorghum genotypes. Salinity is severe abiotic stress that limits plant growth and development in arid… read more here.
Keywords: sorghum genotypes; metabolic changes; tolerance; tolerance sorghum ... See more keywords
Cerebral Metabolic Changes Related to Oxidative Metabolism in a Model of Bacterial Meningitis Induced by Lipopolysaccharide
Sign Up to like & getrecommendations! Published in 2018 at "Neurocritical Care"
DOI: 10.1007/s12028-018-0509-9
Abstract: BackgroundCerebral mitochondrial dysfunction is prominent in the pathophysiology of severe bacterial meningitis. In the present study, we hypothesize that the metabolic changes seen after intracisternal lipopolysaccharide (LPS) injection in a piglet model of meningitis is… read more here.
Keywords: meningitis; lps injection; metabolic changes; oxidative metabolism ... See more keywords
Dynamic species-specific metabolic changes in the trees exposed to chronic N+S additions at the Bear Brook Watershed in Maine, USA
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Forest Science"
DOI: 10.1007/s13595-019-0808-0
Abstract: Key messageRed spruce (Picea rubens Sarg.) and American beech (Fagus grandifolia Ehrh.) nutritional imbalances observed during 1998–2000 in response to nitrogen additions beginning in 1989 at Bear Brook Watershed in Maine, USA, were reversed by… read more here.
Keywords: metabolic changes; watershed maine; species specific; maine usa ... See more keywords
Metabolic changes in tumor cells and tumor-associated macrophages: A mutual relationship.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.10.037
Abstract: In order to adapt to the reduced availability of nutrients and oxygen in the tumor microenvironment and the increased requirements of energy and building blocks necessary for maintaining their high proliferation rate, malignant cells undergo… read more here.
Keywords: tumor associated; metabolic changes; metabolism; tumor cells ... See more keywords
Metabolic Changes Accompanying Spermatogonial Stem Cell Differentiation.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental cell"
DOI: 10.1016/j.devcel.2020.01.014
Abstract: Male fertility is driven by spermatogonial stem cells (SSCs) that self-renew while also giving rise to differentiating spermatogonia. Spermatogonial transitions are accompanied by a shift in gene expression, however, whether equivalent changes in metabolism occur… read more here.
Keywords: accompanying spermatogonial; metabolic changes; spermatogonial stem; changes accompanying ... See more keywords
Pyrogens, a polypeptide produces fever by metabolic changes in hypothalamus: Mechanisms and detections.
Sign Up to like & getrecommendations! Published in 2018 at "Immunology letters"
DOI: 10.1016/j.imlet.2018.10.006
Abstract: Fever is one of the cardinal symptoms of onset of an infection or inflammation and is the common clinical indicator for medical consultation in mammalian host worldwide. Simply, fever manifested with elevation of body temperature… read more here.
Keywords: polypeptide produces; pyrogens polypeptide; changes hypothalamus; metabolic changes ... See more keywords
CCCTC‐Binding Factor Translates Interleukin 2‐ and &agr;‐Ketoglutarate‐Sensitive Metabolic Changes in T Cells into Context‐Dependent Gene Programs
Sign Up to like & getrecommendations! Published in 2017 at "Immunity"
DOI: 10.1016/j.immuni.2017.07.015
Abstract: &NA; Despite considerable research connecting cellular metabolism with differentiation decisions, the underlying mechanisms that translate metabolite‐sensitive activities into unique gene programs are still unclear. We found that aspects of the interleukin‐2 (IL‐2)‐sensitive effector gene program… read more here.
Keywords: sensitive metabolic; gene programs; metabolic changes; agr sensitive ... See more keywords
Imaging Acute Metabolic Changes in Patients with Mild Traumatic Brain Injury Using Hyperpolarized [1-13C]Pyruvate
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.101885
Abstract: Summary Traumatic brain injury (TBI) involves complex secondary injury processes following the primary injury. The secondary injury is often associated with rapid metabolic shifts and impaired brain function immediately after the initial tissue damage. Magnetic… read more here.
Keywords: traumatic brain; pyruvate; metabolic changes; brain ... See more keywords
Analytical approaches to assess metabolic changes in psoriasis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2021.114359
Abstract: Psoriasis is one of the most common human skin diseases, although its development is not limited to one tissue, but is associated with autoimmune reactions throughout the body. Overproduction of pro-inflammatory cytokines and growth factors… read more here.
Keywords: changes psoriasis; metabolic changes; approaches assess; analytical approaches ... See more keywords