Revealing the metabolic characteristics of human embryonic stem cells by genome‐scale metabolic modeling
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.13255
Abstract: Embryonic stem cells (ESCs) are characterized by a dual capacity, self‐renewal and pluripotency, which can be regulated by metabolism. A better understanding of ESC metabolism and regulatory mechanisms is pivotal for research into development, ageing,… read more here.
Keywords: genome scale; metabolic characteristics; embryonic stem; stem ... See more keywords
Comparative Metagenomic and Metatranscriptomic Analyses Reveal the Functional Species and Metabolic Characteristics of an Enriched Denitratation Community.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental science & technology"
DOI: 10.1021/acs.est.0c03164
Abstract: Nitrite supply for mainstream anammox via denitratation has attracted increasing attention. The functional species responsible for denitratation and their metabolic characteristics were unravelled in this study. A highly stable denitratation community was enriched from activated… read more here.
Keywords: reduction; denitratation community; functional species; metabolic characteristics ... See more keywords
Metabolic characteristics of Tanshinone I in human liver microsomes and S9 subcellular fractions
Sign Up to like & getrecommendations! Published in 2019 at "Xenobiotica"
DOI: 10.1080/00498254.2018.1432087
Abstract: Abstract Tanshinone I (TSI) is a lipophilic diterpene in Salvia miltiorrhiza with versatile pharmacological activities. However, metabolic pathway of TSI in human is unknown. In this study, we determined major metabolites of TSI using a… read more here.
Keywords: tsi; metabolic characteristics; subcellular fractions; liver microsomes ... See more keywords
Metabolic, structure-activity characteristics of conjugated linolenic acids and their mediated health benefits.
Sign Up to like & getrecommendations! Published in 2023 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2023.2198006
Abstract: Conjugated linolenic acid (CLnA) is a mixture of octadecenoic acid with multiple positional and geometric isomers (including four 9, 11, 13-C18:3 isomers and three 8, 10, 12-C18:3 isomers) that is mainly present in plant seeds.… read more here.
Keywords: structure; conjugated linolenic; health benefits; metabolic characteristics ... See more keywords
Unveiling metabolic characteristics of an uncultured Gammaproteobacterium responsible for in situ PAH biodegradation in petroleum polluted soil.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental microbiology"
DOI: 10.1111/1462-2920.15814
Abstract: Exploring the metabolic characteristics of indigenous PAH degraders is critical to understanding the PAH bioremediation mechanism in the natural environment. While stable-isotopic probing (SIP) is a viable method to identify functional microorganisms in complex environments,… read more here.
Keywords: characteristics uncultured; biodegradation; metabolic characteristics; uncultured gammaproteobacterium ... See more keywords
The clinical and metabolic characteristics of children and adolescents with hypothalamic dysfunction: A single‐centre study from China
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Endocrinology"
DOI: 10.1111/cen.14814
Abstract: Hypothalamic dysfunction is characterized by complex aetiologies, multiple forms of onset and various clinical symptoms. This study aims to explore the clinical and metabolic characteristics of hypothalamic dysfunction in Chinese children and adolescents. read more here.
Keywords: hypothalamic dysfunction; clinical metabolic; metabolic characteristics; dysfunction ... See more keywords
m1A methylation modification patterns and metabolic characteristics in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "BMC Gastroenterology"
DOI: 10.1186/s12876-022-02160-w
Abstract: Background The dysregulation of RNA methylation has been demonstrated to contribute to tumorigenicity and progression in recent years. However, the alteration of N1-methyladenosine (m1A) methylation and its role in hepatocellular carcinoma (HCC) remain unclear. Methods… read more here.
Keywords: modification patterns; m1a methylation; metabolic characteristics; modification ... See more keywords
Metabolic characteristics and markers in viable but nonculturable state of Pseudomonas aeruginosa induced by chlorine stress.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental research"
DOI: 10.2139/ssrn.4149395
Abstract: Many Gram-negative pathogens enter the viable but nonculturable (VBNC) state to resist external environmental stress (such as disinfection). However, little is known about the metabolic properties, especially for the metabolic markers, of VBNC bacteria, which… read more here.
Keywords: viable nonculturable; chlorine stress; vbnc bacteria; metabolic characteristics ... See more keywords
Clinical and Metabolic Characteristics of Non-Alcoholic Fatty Liver Disease Patients in Saudi Arabia: Data from the Systematic Observatory Liver Disease (SOLID) Registry
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"
DOI: 10.2147/dmso.s300051
Abstract: Background and Aims The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing in Saudi Arabia (SA), but descriptions of the clinical and metabolic characteristics of these patients are limited. The present study aims to… read more here.
Keywords: metabolic characteristics; disease; non alcoholic; alcoholic fatty ... See more keywords
Metabolic Characteristics of SM-1, a Novel PAC-1 Derivative, in Human Liver Microsomes
Sign Up to like & getrecommendations! Published in 2021 at "Current Pharmaceutical Analysis"
DOI: 10.2174/1573412917666210302145158
Abstract: SM-1 is a new synthetic small molecule compound with antitumor activity. The metabolism of SM-1 is a key parameter that needs to be evaluated to provide further insight into drug safety and efficacy in the… read more here.
Keywords: metabolic characteristics; novel pac; characteristics novel; liver microsomes ... See more keywords
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsuficiency.
Sign Up to like & getrecommendations! Published in 2022 at "Haematologica"
DOI: 10.3324/haematol.2022.279437
Abstract: Mono-Allelic germline disruptions of the transcription factor GATA2 result in a propensity for developing myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) affecting more than 85% of carriers. How a partial loss of GATA2 functionality… read more here.
Keywords: cellular metabolic; metabolic characteristics; gata2; pre leukemic ... See more keywords