PHB Associates with the HIRA Complex to Control an Epigenetic-Metabolic Circuit in Human ESCs.
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DOI: 10.1016/j.stem.2016.11.002
Abstract: The chromatin landscape and cellular metabolism both contribute to cell fate determination, but their interplay remains poorly understood. Using genome-wide siRNA screening, we have identified prohibitin (PHB) as an essential factor in self-renewal of human embryonic… read more here.
Keywords: control; metabolic circuit; phb; hira complex ... See more keywords