Not only metformin, but also D-allulose, alleviates metabolic disturbance and cognitive decline in prediabetic rats.
Sign Up to like & getrecommendations! Published in 2020 at "Nutritional neuroscience"
DOI: 10.1080/1028415x.2020.1840050
Abstract: BACKGROUND Prediabetes can be characterized as obesity with metabolic disturbance, leading to cognitive decline and brain pathologies. D-allulose administration in obese animals decreased metabolic disturbance. However, the comparative effects of D-allulose and metformin on cognition… read more here.
Keywords: prediabetic rats; cognitive decline; metabolic disturbance; brain ... See more keywords
Abstract 3006: Metabolomic signatures of metabolic disturbance and inflammation in relation to colorectal cancer risk
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DOI: 10.1158/1538-7445.am2023-3006
Abstract: Background: Metabolic disturbance and inflammation may explain observed associations between higher body mass index (BMI) and increased risk of colorectal cancer (CRC); however, the underlying mechanisms are not fully understood. Objectives: We characterized individual plasma… read more here.
Keywords: disturbance; metabolic disturbance; metabolomic signatures; disturbance inflammation ... See more keywords
Melatonin reverses tumor necrosis factor-alpha-induced metabolic disturbance of human nucleus pulposus cells via MTNR1B/Gαi2/YAP signaling
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DOI: 10.7150/ijbs.65973
Abstract: Background: Intervertebral disc degeneration (IDD), the main cause of low back pain, is closely related to the inflammatory microenvironment in the nucleus pulposus (NP). Tumor necrosis factor-α (TNF-α) plays an important role in inflammation-related metabolic… read more here.
Keywords: metabolic disturbance; tnf; melatonin; tumor necrosis ... See more keywords