Insect models of central nervous system energy metabolism and its links to behavior
Sign Up to like & getrecommendations! Published in 2018 at "Glia"
DOI: 10.1002/glia.23235
Abstract: Neuronal activity requires a vast amount of energy. Energy use in the brain is spatially and temporally dynamic, which reflects the changing activity of the neuronal circuits and might be important for modulating neuronal output.… read more here.
Keywords: energy; metabolism; metabolic dynamics; nervous system ... See more keywords
Application of Stable Isotope Tracing to Elucidate Metabolic Dynamics During Yarrowia lipolytica α-Ionone Fermentation
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DOI: 10.1016/j.isci.2020.100854
Abstract: Summary Targeted metabolite analysis in combination with 13C-tracing is a convenient strategy to determine pathway activity in biological systems; however, metabolite analysis is limited by challenges in separating and detecting pathway intermediates with current chromatographic… read more here.
Keywords: application stable; metabolic dynamics; fermentation; ionone ... See more keywords
D2O-Probed Raman Microspectroscopy Distinguishes the Metabolic Dynamics of Macromolecules in Organellar Anticancer Drug Response.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c03925
Abstract: To profile the metabolic dynamics responding to drugs at the single-cell/organelle resolution, rapid and economical mechanism-revealing methods are required. Here, we introduced D2O-probed Raman microspectroscopy in combination with the multivariate curve resolution-alternating least squares (MCR-ALS… read more here.
Keywords: d2o probed; probed raman; response; metabolic dynamics ... See more keywords
Deuterium-labeled Raman tracking of glucose accumulation and protein metabolic dynamics in Aspergillus nidulans hyphal tips
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80270-9
Abstract: Filamentous fungi grow exclusively at their tips, where many growth-related fungal processes, such as enzyme secretion and invasion into host cells, take place. Hyphal tips are also a site of active metabolism. Understanding metabolic dynamics… read more here.
Keywords: deuterium; glucose accumulation; metabolic dynamics; deuterium labeled ... See more keywords
Spatiotemporal monitoring of intracellular metabolic dynamics by resonance Raman microscopy with isotope labeling
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra02803g
Abstract: Cellular metabolites are valuable in a diverse range of applications. For example, the unicellular green alga Haematococcus lacustris produces as a secondary metabolite the carotenoid pigment astaxanthin (AXT), which is widely used in nutraceutical, cosmetic,… read more here.
Keywords: spatiotemporal monitoring; metabolic dynamics; resonance raman; microscopy ... See more keywords
Uncovering in vivo biochemical patterns from time-series metabolic dynamics
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0268394
Abstract: System biology relies on holistic biomolecule measurements, and untangling biochemical networks requires time-series metabolomics profiling. With current metabolomic approaches, time-series measurements can be taken for hundreds of metabolic features, which decode underlying metabolic regulation. Such… read more here.
Keywords: metabolic dynamics; time; series metabolic; time series ... See more keywords
Metabolic Dynamics of Ecosystems Realizing Steady Log-Uniform Distributions: The Case of Commodities in Shops
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DOI: 10.3390/e22030267
Abstract: From the viewpoint of statistical physics, ecosystems in the real world are very attractive targets of research as examples of far-from thermal equilibrium systems where various kinds of components are coming in and out continuously… read more here.
Keywords: log uniform; metabolic dynamics; ecosystems realizing; dynamics ecosystems ... See more keywords
Metabolic Dynamics in Short- and Long-Term Microgravity in Human Primary Macrophages
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22136752
Abstract: Microgravity acts on cellular systems on several levels. Cells of the immune system especially react rapidly to changes in gravity. In this study, we performed a correlative metabolomics analysis on short-term and long-term microgravity effects… read more here.
Keywords: term; long term; metabolic dynamics; term microgravity ... See more keywords