Early cardiomyopathy without severe metabolic dysregulation in a patient with cblB‐type methylmalonic acidemia
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1971
Abstract: Cardiomyopathy is a known complication of organic acidemias but generally thought to be secondary to poor metabolic control. read more here.
Keywords: cardiomyopathy without; without severe; metabolic dysregulation; early cardiomyopathy ... See more keywords
Antecedent ADHD, dementia, and metabolic dysregulation: A U.S. based cohort analysis
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2017.08.005
Abstract: Introduction: Epidemiological and genetic studies have reported a link between antecedent ADHD and dementia. The underpinning mechanisms of these associations are not known and have generated considerable speculation. Methods: We have extracted hospitalization discharge data… read more here.
Keywords: dementia; metabolic dysregulation; adhd dementia; antecedent adhd ... See more keywords
Red Wine High-Molecular-Weight Polyphenolic Complex Ameliorates High-Fat Diet-Induced Metabolic Dysregulation and Perturbation in Gut Microbiota in Mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c06459
Abstract: Red wine polyphenolic complexes have attracted increasing attention as potential modulators of human metabolic disease risk. Our previous study discovered that red wine high-molecular-weight polymeric polyphenolic complexes (HPPCs) could inhibit key metabolic syndrome-associated enzymes and… read more here.
Keywords: red wine; polyphenolic; metabolic dysregulation; induced metabolic ... See more keywords
JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis
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DOI: 10.1038/s41375-018-0354-z
Abstract: Abnormal metabolism is a fundamental hallmark of cancer and represents a therapeutic opportunity, yet its regulation by oncogenes remains poorly understood. Here, we uncover that JMJD1C, a jumonji C (JmjC)-containing H3K9 demethylase, is a critical… read more here.
Keywords: dysregulation contributes; metabolic dysregulation; mediated metabolic; jmjd1c ... See more keywords
Metabolic dysregulation into fibrosis
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DOI: 10.1126/science.366.6472.1467-s
Abstract: Fibrosis Excessive fibrosis around alveoli, tiny air sacs that promote gas exchange, prevents the lungs from expanding properly. Yin et al. found that the glycolytic enzyme hexokinase 2 (HK2) was abundant in lung fibroblasts from… read more here.
Keywords: dysregulation fibrosis; fibrosis; metabolic dysregulation; hk2 ... See more keywords
Peroxisome proliferator-activated receptor gamma deacetylation: a promising therapeutic strategy to control metabolic dysregulation in obesity.
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733031
Abstract: Obesity was recognized as a disease only in 1998. Currently, obesity has reached epidemic levels affecting half of the US population. Obesity, which is characterized by increased body mass index (BMI), body fat distribution and… read more here.
Keywords: deacetylation; physiology; metabolic dysregulation; mice ... See more keywords
Abstract 3122: Metabolic dysregulation and risk of non-alcoholic fatty liver disease in Mexican adults
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Trials"
DOI: 10.1158/1538-7445.am2020-3122
Abstract: Background: Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease and the fastest growing cause of cirrhosis in the United States (U.S.). This is very concerning because NAFLD-related cirrhosis is associated… read more here.
Keywords: risk; metabolic dysregulation; disease; cancer ... See more keywords
DNMT3A and TET2; Potential Estimates of Generic DNA Methylation in Children and Adolescents with Obesity; Relation to Metabolic Dysregulation
Sign Up to like & getrecommendations! Published in 2022 at "Hormone Research in Paediatrics"
DOI: 10.1159/000521701
Abstract: Introduction: The role of DNA methylation in metabolic dysregulation is emerging. However, the functional role of methylation in obesity and metabolic dysregulation is poorly understood. Aim: The aim of this study was to compare DNA… read more here.
Keywords: children adolescents; adolescents obesity; metabolic dysregulation; dnmt3a ... See more keywords
Precise Metabolomics Defines Systemic Metabolic Dysregulation Distinct to Acute Myocardial Infarction Associated With Diabetes
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DOI: 10.1161/atvbaha.122.318871
Abstract: Background: Acute myocardial infarction (AMI) is a leading cause of death and disability. Diabetes is an important risk factor and a common comorbidity in AMI patients. The higher mortality risk of diabetes-AMI relative to nondiabetes-AMI… read more here.
Keywords: myocardial infarction; diabetes ami; metabolic dysregulation; acute myocardial ... See more keywords
Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension
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DOI: 10.1172/jci.insight.145346
Abstract: BACKGROUND Idiopathic intracranial hypertension (IIH) is a condition predominantly affecting obese women of reproductive age. Recent evidence suggests that IIH is a disease of metabolic dysregulation, androgen excess, and an increased risk of cardiovascular morbidity.… read more here.
Keywords: metabolic dysregulation; idiopathic intracranial; disease; intracranial hypertension ... See more keywords
Metabolic dysregulation and cancer mortality in a national cohort of blacks and whites
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DOI: 10.1186/s12885-017-3807-2
Abstract: BackgroundWe examined the association between metabolic dysregulation and cancer mortality in a prospective cohort of Black and White adults.MethodsA total of 25,038 Black and White adults were included in the analysis. Metabolic dysregulation was defined in… read more here.
Keywords: cancer; metabolic dysregulation; dysregulation cancer; cancer mortality ... See more keywords