Identification of the Consistently Altered Metabolic Targets in Human Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2017.05.004
Abstract: Background & Aims Cancer cells rely on metabolic alterations to enhance proliferation and survival. Metabolic gene alterations that repeatedly occur in liver cancer are largely unknown. We aimed to identify metabolic genes that are consistently… read more here.
Keywords: hepatocellular carcinoma; metabolic targets; metabolic genes; consistently altered ... See more keywords
Natural selection of immune and metabolic genes associated with health in two lowland Bolivian populations
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2207544120
Abstract: Significance Humans have adapted to diverse environments, but few studies have linked regions of the genome with evidence of selection to phenotypes. We generated an integrative dataset of genomic, transcriptomic, and biomarker data for the… read more here.
Keywords: selection immune; genes associated; metabolic genes; natural selection ... See more keywords
Underexplored viral auxiliary metabolic genes in soil: Diversity and eco-evolutionary significance.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental microbiology"
DOI: 10.1111/1462-2920.16329
Abstract: Bacterial viruses are the most abundant biological entities in soil ecosystems. Owing to the advent of metagenomics and viromics approaches, an ever-increasing diversity of virus-encoded auxiliary metabolic genes (AMGs) have been identified in soils, including… read more here.
Keywords: auxiliary metabolic; viral amgs; eco evolutionary; diversity ... See more keywords
Androgen-mediated perturbation of the hepatic circadian system through epigenetic modulation promotes NAFLD in PCOS mice.
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac127
Abstract: In women, excess androgen causes polycystic ovary syndrome (PCOS), a common fertility disorder with comorbid metabolic dysfunctions including diabetes, obesity, and nonalcoholic fatty-liver disease (NAFLD). Using a PCOS mouse model, this study shows that chronic… read more here.
Keywords: system; androgen mediated; metabolic genes; androgen ... See more keywords
The role of multiple metabolic genes in predicting the overall survival of colorectal cancer: A study based on TCGA and GEO databases
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0251323
Abstract: The recent advances in gene chip technology have led to the identification of multiple metabolism-related genes that are closely associated with colorectal cancer (CRC). Nevertheless, none of these genes could accurately diagnose or predict CRC.… read more here.
Keywords: metabolic genes; prognosis; prognostic model; model ... See more keywords
Prognostic Signatures of Metabolic Genes and Metabolism-Related Long Non-coding RNAs Accurately Predict Overall Survival for Osteosarcoma Patients
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.644220
Abstract: In this study, we identified eight survival-related metabolic genes in differentially expressed metabolic genes by univariate Cox regression analysis based on the therapeutically applicable research to generate effective treatments (n = 84) data set and… read more here.
Keywords: metabolism; metabolic genes; metabolism related; signature ... See more keywords
The Depletion of Carbohydrate Metabolic Genes in the Gut Microbiome Contributes to the Transition From Central Obesity to Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.747646
Abstract: Obesity, especially central obesity, is a strong risk factor for developing type 2 diabetes (T2D). However, the mechanism underlying the progression from central obesity to T2D remains unknown. Therefore, we analyzed the gut microbial profiles… read more here.
Keywords: metabolic genes; type diabetes; central obesity; obesity ... See more keywords
N1-methyladenosine methylation-related metabolic genes signature and subtypes for predicting prognosis and immune microenvironment in osteosarcoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.993594
Abstract: N1-methyladenosine methylation (m1A), as an important RNA methylation modification, regulates the development of many tumours. Metabolic reprogramming is one of the important features of tumour cells, and it plays a crucial role in tumour development… read more here.
Keywords: methylation; related metabolic; signature; methyladenosine methylation ... See more keywords
Comparative Transcriptomics and Methylomics Reveal Adaptive Responses of Digestive and Metabolic Genes to Dietary Shift in Giant and Red Pandas
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13081446
Abstract: Both the giant panda (Ailuropoda melanoleuca) and red panda (Ailurus fulgens) belong to the order Carnivora, but have changed their dietary habits to eating bamboo exclusively. The convergent evolution characteristics of their morphology, genome and… read more here.
Keywords: digestive metabolic; adaptive responses; dietary shift; two pandas ... See more keywords
ZmFAR1 and ZmABCG26 Regulated by microRNA Are Essential for Lipid Metabolism in Maize Anther
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22157916
Abstract: The function and regulation of lipid metabolic genes are essential for plant male reproduction. However, expression regulation of lipid metabolic genic male sterility (GMS) genes by noncoding RNAs is largely unclear. Here, we systematically predicted… read more here.
Keywords: metabolic genes; zmfar1; zmabcg26 zmfar1; zmfar1 zmabcg26 ... See more keywords
Profiles of Cytokinins Metabolic Genes and Endogenous Cytokinins Dynamics during Shoot Multiplication In Vitro of Phalaenopsis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073755
Abstract: Shoot multiplication induced by exogenous cytokinins (CKs) has been commonly used in Phalaenopsis micropropagation for commercial production. Despite this, mechanisms of CKs action on shoot multiplication remain unclear in Phalaenopsis. In this study, we first… read more here.
Keywords: metabolic genes; cks metabolic; genes endogenous; phalaenopsis ... See more keywords