In vivo metabolic imaging and monitoring of brown and beige fat.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biophotonics"
DOI: 10.1002/jbio.201800019
Abstract: Activation of the thermogenic brown and beige fat is an effective means to increasing whole-body energy expenditure. In this work, a unique label-free method was developed to quantitatively assess the metabolism and thermogenesis of mouse… read more here.
Keywords: imaging monitoring; beige fat; brown beige; monitoring brown ... See more keywords
Whole‐Abdomen Metabolic Imaging of Healthy Volunteers Using Hyperpolarized [1‐13C]pyruvate MRI
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28196
Abstract: Hyperpolarized 13C MRI quantitatively measures enzyme‐catalyzed metabolism in cancer and metabolic diseases. Whole‐abdomen imaging will permit dynamic metabolic imaging of several abdominal organs simultaneously in healthy and diseased subjects. read more here.
Keywords: abdomen metabolic; metabolic imaging; healthy volunteers; hyperpolarized 13c ... See more keywords
Spectrally selective three‐dimensional dynamic balanced steady‐state free precession for hyperpolarized C‐13 metabolic imaging with spectrally selective radiofrequency pulses
Sign Up to like & getrecommendations! Published in 2017 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.26480
Abstract: Balanced steady‐state free precession (bSSFP) sequences can provide superior signal‐to‐noise ratio efficiency for hyperpolarized (HP) carbon‐13 (13C) magnetic resonance imaging by efficiently utilizing the nonrecoverable magnetization, but managing their spectral response is challenging in the… read more here.
Keywords: free precession; balanced steady; steady state; state free ... See more keywords
Deuterium metabolic imaging of the human brain in vivo at 7 T
Sign Up to like & getrecommendations! Published in 2022 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.29439
Abstract: To explore the potential of deuterium metabolic imaging (DMI) in the human brain in vivo at 7 T, using a multi‐element deuterium (2H) RF coil for 3D volume coverage. read more here.
Keywords: deuterium metabolic; metabolic imaging; brain vivo; deuterium ... See more keywords
The Utility of Metabolic Imaging in Patients with Obscure Abdominal Pain: Is it Required?
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Surgery"
DOI: 10.1007/s12262-020-02111-3
Abstract: Abdominal pain is one of the most frequent and worrisome complaints that brings a patient to the hospital. Patients with undiagnosed abdominal pain usually undergo a battery of investigations, while remaining dissatisfied. Since glucose metabolic… read more here.
Keywords: utility; abdominal pain; fdg pet; metabolic imaging ... See more keywords
Deuterium metabolic imaging in the human brain at 9.4 Tesla with high spatial and temporal resolution
Sign Up to like & getrecommendations! Published in 2021 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2021.118639
Abstract: PURPOSE To present first highly spatially resolved deuterium metabolic imaging (DMI) measurements of the human brain acquired with a dedicated coil design and a fast chemical shift imaging (CSI) sequence at an ultrahigh field strength… read more here.
Keywords: resolution; temporal resolution; deuterium metabolic; human brain ... See more keywords
NIMG-57. SERIAL HYPERPOLARIZED 13C PYRUVATE AND 1H METABOLIC IMAGING IN RECURRENT HIGH-GRADE GLIOMA
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.726
Abstract: Hyperpolarized (HP) 13C MRI is a novel metabolic imaging that allows for real time in vivo probing of pathway-specific metabolic processes relevant to gliomas. The first human brain application reports were published recently. In this… read more here.
Keywords: glioma; pyruvate; lactate conversion; hyperpolarized 13c ... See more keywords
Structural and Metabolic Imaging After Short-term Use of the Balance Goggles System in Glaucoma Patients: A Pilot Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Glaucoma"
DOI: 10.1097/ijg.0000000000002066
Abstract: Précis: Short-term use of the Balance Goggles System (BGS) in glaucoma patients was not associated with the observable changes in conventional ocular coherence tomography (OCT) imaging, but metabolic imaging using peripapillary flavoprotein fluorescence (FPF) may… read more here.
Keywords: metabolic imaging; glaucoma; term use; short term ... See more keywords
New metabolic imaging tools in neuro-oncology.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000000758
Abstract: PURPOSE OF REVIEW The current treatment of gliomas dovetails results of decades-old clinical trials with modern trends in chemotherapy. Molecular characterization now plays a pivotal role, and IDH mutations are key characteristics and the subject… read more here.
Keywords: imaging tools; warburg effect; metabolic imaging; oncology ... See more keywords
Metabolic imaging using hyperpolarized 13C‐pyruvate to assess sensitivity to the B‐Raf inhibitor vemurafenib in melanoma cells and xenografts
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14890
Abstract: Nearly all melanoma patients with a BRAF‐activating mutation will develop resistance after an initial clinical benefit from BRAF inhibition (BRAFi). The aim of this work is to evaluate whether metabolic imaging using hyperpolarized (HP) 13C… read more here.
Keywords: melanoma; pyruvate; conversion; imaging using ... See more keywords
Mechanobiology of Cartilage Impact via Real-Time Metabolic Imaging.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4047534
Abstract: Cartilage loading is important in both structural and biological contexts, with overloading known to cause osteoarthritis. Cellular metabolism, which can be evaluated through the relative measures of glycolysis and oxidative phosphorylation, is important in disease… read more here.
Keywords: fluorescence; impact; time; redox ratio ... See more keywords