Pan-cancer analysis of tumor metabolic landscape associated with genomic alterations
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DOI: 10.1186/s12943-018-0895-9
Abstract: Although metabolic alterations are one of the hallmarks of cancer, there is a lack of understanding of how metabolic landscape is reconstituted according to cancer progression and which genetic alterations underlie its heterogeneity within cancer… read more here.
Keywords: cancer; genetic alterations; metabolic landscape; tumor metabolic ... See more keywords
The Metabolic Landscape in Osteoarthritis
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DOI: 10.14336/ad.2021.1228
Abstract: Articular cartilage function depends on the temporal and zonal distribution of coordinated metabolic regulation in chondrocytes. Emerging evidence shows the importance of cellular metabolism in the molecular control of the cartilage and its dysregulation in… read more here.
Keywords: metabolism; cartilage; metabolic landscape; landscape osteoarthritis ... See more keywords
Metabolic Landscape of Bronchoalveolar Lavage Fluid in Coronavirus Disease 2019 at Single Cell Resolution
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.829760
Abstract: Abnormal function of immune cells is one of the key mechanisms leading to severe clinical symptoms in coronavirus disease 2019 patients, and metabolic pathways can destroy the function of the immune system by affecting innate… read more here.
Keywords: coronavirus disease; metabolic landscape; single cell; immune cells ... See more keywords
The Lipid Metabolic Landscape of Cancers and New Therapeutic Perspectives
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DOI: 10.3389/fonc.2020.605154
Abstract: Lipid metabolism reprograming, as a hallmark of malignancy, has received renewed interest in recent years in such areas as energy sources, cell membrane components, and signaling molecules involved in the rapid tumor growth and the… read more here.
Keywords: landscape cancers; metabolic landscape; lipid metabolic; lipid metabolism ... See more keywords
An Update on the Metabolic Landscape of Oncogenic Viruses
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DOI: 10.3390/cancers14235742
Abstract: Simple Summary Cancer cells amplify in an uncontrolled fashion. The resulting tumor and metastases need to ensure their survival in the body. To achieve this, cancer cells display increased nutritional needs and an altered metabolism.… read more here.
Keywords: cancer; update metabolic; metabolic landscape; metabolic changes ... See more keywords
On the Relevance of Soft Tissue Sarcomas Metabolic Landscape Mapping
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DOI: 10.3390/ijms231911430
Abstract: Soft tissue sarcomas (STS) prognosis is disappointing, with current treatment strategies being based on a “fit for all” principle and not taking distinct sarcoma subtypes specificities and genetic/metabolic differences into consideration. The paucity of precision… read more here.
Keywords: metabolic landscape; relevance soft; soft tissue; tissue sarcomas ... See more keywords