Lytic Cell Death in Metabolic Liver Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2020.04.001
Abstract: Regulated cell death is intrinsically associated with inflammatory liver disease and is pivotal in governing outcomes of metabolic liver disease. Different types of cell death may coexist in the progression of metabolic liver disease to… read more here.
Keywords: liver disease; death; metabolic liver; cell death ... See more keywords
The rate of hepatic artery complications is higher in pediatric liver transplant recipients with metabolic liver diseases than with biliary atresia.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2018.04.029
Abstract: BACKGROUND Liver transplantation (LT) is an excellent treatment option for patients with biliary atresia (BA) who fail portoenterostomy surgery. LT is also increasingly performed in patients with metabolic liver diseases. This study compared the outcomes… read more here.
Keywords: liver diseases; artery complications; metabolic liver; liver ... See more keywords
Clinical and biochemical footprints of inherited metabolic diseases. II. Metabolic liver diseases.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular genetics and metabolism"
DOI: 10.1016/j.ymgme.2019.04.002
Abstract: Inherited metabolic diseases account for about one third of pediatric patients with hepatomegaly, acute liver failure, cirrhosis or cholestasis. Specifically for pediatric acute liver failure, they account for 10-15% of cases, with a mortality of… read more here.
Keywords: liver failure; metabolic diseases; acute liver; metabolic liver ... See more keywords
Prof Jörn Schattenberg sheds light on key treatment and diagnostic approaches to nonalcoholic steatohepatitis (NASH)
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2020.1721150
Abstract: I am the Director of the Metabolic Liver Research Center and Professor of Medicine at the University Medical Center Mainz, Germany. I started to work on NASH in 2002 during my postdoctoral education at the… read more here.
Keywords: schattenberg sheds; medicine; prof schattenberg; treatment ... See more keywords
A perspective on RNA interference-based therapeutics for metabolic liver diseases
Sign Up to like & getrecommendations! Published in 2021 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2021.1879792
Abstract: ABSTRACT Introduction: Therapeutic oligonucleotides have emerged as a promising new class of drug that could silence undruggable targets; they can potentially treat metabolic liver diseases such as nonalcoholic fatty liver disease (NAFLD), hereditary hemochromatosis and… read more here.
Keywords: liver diseases; rna interference; metabolic liver; perspective rna ... See more keywords
Abstract 2369: Targeting peroxiredoxin 2 prevents hepatocellular carcinoma development in metabolic liver disease
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-2369
Abstract: HCC is the third most common cause of cancer-related death and the leading cause of death among cirrhotic patients. While several treatments for HCC have been approved, chemopreventive strategies for HCC are lacking. Aiming to… read more here.
Keywords: disease; cancer; prdx2; metabolic liver ... See more keywords
Pectin in Metabolic Liver Disease
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu15010157
Abstract: Alterations in the composition of the gut microbiota (dysbiosis) are observed in nutritional liver diseases, including non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD) and have been shown to be associated with the… read more here.
Keywords: pectin metabolic; liver disease; liver; metabolic liver ... See more keywords
Challenges in pediatric inherited/metabolic liver disease: Focus on the disease spectrum, diagnosis and management of relatively common disorders
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v29.i14.2114
Abstract: The clinical scenario of pediatric liver disease is becoming more intricate due to changes in the disease spectrum, in which an increasing number of inherited/ metabolic liver diseases are reported, while infectious diseases show a… read more here.
Keywords: metabolic liver; disease spectrum; diagnosis; liver disease ... See more keywords
Immune remodulation in pediatric inherited metabolic liver diseases
Sign Up to like & getrecommendations! Published in 2024 at "World Journal of Hepatology"
DOI: 10.4254/wjh.v16.i9.1258
Abstract: Inherited metabolic liver diseases arise from genetic mutations that lead to disruptions in liver metabolic pathways and are predominantly observed in pediatric populations. The spectrum of genetic metabolic liver disorders is diverse, encompassing a range… read more here.
Keywords: liver diseases; metabolic liver; immune remodulation; liver ... See more keywords