Articles with "metabolic pathway" as a keyword



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Comprehensive analysis of metabolic pathway activity subtypes derived prognostic signature in hepatocellular carcinoma

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Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.4858

Abstract: Metabolic reprogramming is one of the hallmarks of cancer, but metabolic pathway activity‐related subtypes of hepatocellular carcinoma (HCC) have not been identified. read more here.

Keywords: hepatocellular carcinoma; metabolic pathway; pathway activity;
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Cellulosimicrobium fucosivorans sp. nov., isolated from San Elijo Lagoon, contains a fucose metabolic pathway linked to carotenoid production.

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Published in 2021 at "Archives of microbiology"

DOI: 10.1007/s00203-021-02443-y

Abstract: Cellulosimicrobium strain SE3T was isolated from the San Elijo coastal lagoon near San Diego. A whole genome-based phylogenetic comparison shows great heterogeneity within the Cellulosimicrobium genus. Based on average nucleotide identity, whole genome-based comparison, and… read more here.

Keywords: metabolic pathway; lagoon; fucose metabolic; cellulosimicrobium ... See more keywords
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Analysis of catecholamines and related compounds in one whole metabolic pathway with high performance liquid chromatography based on derivatization

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Published in 2019 at "Arabian Journal of Chemistry"

DOI: 10.1016/j.arabjc.2014.11.038

Abstract: Abstract The simultaneous determination of Tyr, catecholamines and their metabolites in one whole metabolic pathway using high performance liquid chromatography coupled with fluorescence detection (HPLC–FLD) based on pre-column derivatization has been achieved successfully. 1,3,5,7-Tetramethyl-8-(N-hydroxysuccinimidyl butyric… read more here.

Keywords: metabolic pathway; whole metabolic; performance liquid; one whole ... See more keywords
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Monitoring metabolic pathway alterations in Escherichia coli due to applied potentials in microbial electrochemical system.

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Published in 2020 at "Bioelectrochemistry"

DOI: 10.1016/j.bioelechem.2020.107530

Abstract: Redox potential is one of the key regulators in determining the fate of the metabolic pathways of biocatalysts and of their associated product synthesis in microbial electrochemical systems. In the present study, the influence of… read more here.

Keywords: system; applied potentials; metabolic pathway; pathway alterations ... See more keywords
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An efficient tool for metabolic pathway construction and gene integration for Aspergillus niger.

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Published in 2017 at "Bioresource technology"

DOI: 10.1016/j.biortech.2017.05.004

Abstract: Metabolic engineering requires functional genetic tools for easy and quick generation of multiple pathway variants. A genetic engineering toolbox for A. niger is presented, which facilitates the generation of strains carrying heterologous expression cassettes at… read more here.

Keywords: efficient tool; metabolic pathway; integration; construction ... See more keywords
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Enhanced production of 2,3-butanediol from xylose by combinatorial engineering of xylose metabolic pathway and cofactor regeneration in pyruvate decarboxylase-deficient Saccharomyces cerevisiae.

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Published in 2017 at "Bioresource technology"

DOI: 10.1016/j.biortech.2017.06.034

Abstract: The aim of this study was to produce 2,3-butanediol (2,3-BDO) from xylose efficiently by modulation of the xylose metabolic pathway in engineered Saccharomyces cerevisiae. Expression of the Scheffersomyces stipitis transaldolase and NADH-preferring xylose reductase in… read more here.

Keywords: pyruvate decarboxylase; saccharomyces cerevisiae; metabolic pathway; decarboxylase deficient ... See more keywords
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Insight into SO4(-II)- dependent anaerobic methane oxidation in landfill: Dual-substrates dynamics model, microbial community, function and metabolic pathway.

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Published in 2022 at "Waste management"

DOI: 10.1016/j.wasman.2022.01.032

Abstract: In anaerobic landfill, SO42- could serve as electron receptor for methane oxidation. In theory, concentrations of both methane and SO42- should be related to methane oxidation rate. However, the dynamics process has yet to be… read more here.

Keywords: methane oxidation; oxidation; dependent anaerobic; anaerobic methane ... See more keywords
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Improvement of 1,3-propanediol production using an engineered cyanobacterium, Synechococcus elongatus by optimization of the gene expression level of a synthetic metabolic pathway and production conditions.

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Published in 2017 at "Metabolic engineering"

DOI: 10.1016/j.ymben.2016.12.001

Abstract: The introduction of a synthetic metabolic pathway consisting of multiple genes derived from various organisms enables cyanobacteria to directly produce valuable chemicals from carbon dioxide. We previously constructed a synthetic metabolic pathway composed of genes… read more here.

Keywords: production; metabolic pathway; synthetic metabolic; glycerol ... See more keywords
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Quorum sensing-mediated protein degradation for dynamic metabolic pathway control in Saccharomyces cerevisiae.

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Published in 2021 at "Metabolic engineering"

DOI: 10.1016/j.ymben.2021.01.010

Abstract: Dynamic regulation has been widely applied to optimize metabolic flux distribution. However, compared with prokaryotes, quorum sensing-mediated pathway control is still very limited in Saccharomyces cerevisiae. In this study, we designed quorum sensing-regulated protein degradation… read more here.

Keywords: degradation; metabolic pathway; quorum sensing; protein degradation ... See more keywords
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4″-Sulfation Is the Major Metabolic Pathway of Epigallocatechin-3-gallate in Humans: Characterization of Metabolites, Enzymatic Analysis, and Pharmacokinetic Profiling

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Published in 2022 at "Journal of Agricultural and Food Chemistry"

DOI: 10.1021/acs.jafc.2c02150

Abstract: Epigallocatechin-3-gallate (EGCG), a major green tea polyphenol, has beneficial effects on human health. This study aimed to elucidate the detailed EGCG sulfation process to better understand its phase II metabolism, a process required to maximize… read more here.

Keywords: sulfation; epigallocatechin gallate; metabolic pathway; sulfation major ... See more keywords
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Clarification of Arachidonic Acid Metabolic Pathway Intricacies

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Published in 2021 at "ACS Omega"

DOI: 10.1021/acsomega.1c01952

Abstract: Surrounding inflammation activates phospholipase A2, which cleaves and releases arachidonic acid (ARA) from cell membranes. The four cis double bonds are instrumental in ARA susceptibility to oxidation, resulting in the generation of numerous bioactive metabolites… read more here.

Keywords: metabolic pathway; inflammation; clarification arachidonic; arachidonic acid ... See more keywords