A pilot study: Metabolic profiling of plasma and saliva samples from newly diagnosed glioblastoma patients.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.5857
Abstract: BACKGROUND Despite aggressive treatment, more than 90% of glioblastoma (GBM) patients experience recurrences. GBM response to therapy is currently assessed by imaging techniques and tissue biopsy. However, difficulties with these methods may cause misinterpretation of… read more here.
Keywords: glioblastoma; plasma; study metabolic; metabolic profiling ... See more keywords
Metabolic profiling of liver fat—Limited insights by big data research so far
Sign Up to like & getrecommendations! Published in 2023 at "Obesity"
DOI: 10.1002/oby.23713
Abstract: In a study on a subgroup of the UK Biobank population in this issue of Obesity , the authors addressed the association of 180 blood metabolites (by nuclear magnetic resonance [NMR] spectrometry) with liver fat… read more here.
Keywords: liver; liver fat; fatty acids; density lipoprotein ... See more keywords
Host-Guest Self-Assembled Interfacial Nanoarrays for Precise Metabolic Profiling.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202207190
Abstract: Accurate and rapid metabolic profiling of cerebrospinal fluid (CSF) is urgently needed but remains challenging for clinical diagnosis of central nervous system diseases and biomarker discovery. Matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) holds promise… read more here.
Keywords: platform; based ldi; self assembled; msana based ... See more keywords
Can metabolic profiling provide a new description of osteoarthritis and enable a personalised medicine approach?
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-05106-3
Abstract: Osteoarthritis (OA) is a multifactorial disease contributing to significant disability and economic burden in Western populations. The aetiology of OA remains poorly understood, but is thought to involve genetic, mechanical and environmental factors. Currently, the… read more here.
Keywords: medicine; provide new; personalised medicine; metabolic profiling ... See more keywords
Metabolic profiling of Drosophila melanogaster metamorphosis: a new insight into the central metabolic pathways
Sign Up to like & getrecommendations! Published in 2017 at "Metabolomics"
DOI: 10.1007/s11306-017-1167-1
Abstract: IntroductionMetamorphosis is a complicated process in which cell proliferation, differentiation, and death are orchestrated to form the mature structures of insects. In Drosophila, this process is controlled by ecdysone, a steroid hormone responsible for tissue… read more here.
Keywords: drosophila; central metabolic; metabolic profiling; metabolic pathways ... See more keywords
Metabolic profiling by 1H NMR spectroscopy of saliva shows clear distinction between control and diseased case of periodontitis
Sign Up to like & getrecommendations! Published in 2017 at "Metabolomics"
DOI: 10.1007/s11306-017-1245-4
Abstract: IntroductionPeriodontitis is a chronic, non-reversible inflammatory disease of the oral cavity leading to destruction of periodontal tissues. Thus, the estimation of bacterial metabolite, tissue damage and secretory metabolites of the triggered inflammatory cells likely to… read more here.
Keywords: saliva; metabolic profiling; nmr spectroscopy; case ... See more keywords
Untargeted metabolic profiling reveals distinct patterns of thermal sensitivity in two related notothenioids.
Sign Up to like & getrecommendations! Published in 2018 at "Comparative biochemistry and physiology. Part A, Molecular & integrative physiology"
DOI: 10.1016/j.cbpa.2017.12.012
Abstract: Antarctic marine ectothermal animals may be affected more than temperate species by rising temperatures due to ongoing climate change. Their specialisation on stable cold temperatures makes them vulnerable to even small degrees of warming. Thus,… read more here.
Keywords: amino acid; metabolic profiling; physiology; metabolite profiles ... See more keywords
Pharmacokinetics and comparative metabolic profiling of iridoid enriched fraction of Picrorhiza kurroa - An Ayurvedic Herb.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2016.07.072
Abstract: ETHNO-PHARMACOLOGICAL RELEVANCE Picrosides I, II and apocynin are the main active principles present in the roots and rhizomes of Picrorhiza kurroa Royle ex. Benth (Kutki). Ethno-medicinally, the plant is used for the treatment of liver,… read more here.
Keywords: rat plasma; metabolic profiling; enriched fraction; picrosides apocynin ... See more keywords
Non-invasive urinary metabolomics reveals metabolic profiling of polycystic ovary syndrome and its subtypes.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113262
Abstract: Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder, which affects 4-10 % women of reproductive age. Though accumulating scientific evidence, its pathogenesis remains unclear. In the current study, metabolic profiling as well as diagnostic… read more here.
Keywords: polycystic ovary; metabolic profiling; invasive urinary; non invasive ... See more keywords
Metabolic profiling, histopathological anti-ulcer study, molecular docking and molecular dynamics of ursolic acid isolated from Ocimum forskolei Benth. (family Lamiaceae)
Sign Up to like & getrecommendations! Published in 2020 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2020.03.004
Abstract: Abstract Ocimum forskolei (Habak), Lamiaceae, is an endemic species from Yemen and KSA; where our present study was aimed at investigating the Metabolic profiling coupled with LC HR-MS analysis of the dichloromethane fraction from the… read more here.
Keywords: metabolic profiling; molecular dynamics; ursolic acid; study ... See more keywords
The potential of metabolic profiling for vaccine development.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in immunology"
DOI: 10.1016/j.smim.2018.07.002
Abstract: Recent technological advances have provided deeper insights into the role of small molecules in biological processes. Metabolic profiling has thus entered the arena of -omics studies and rapidly proven its value both as stand-alone and… read more here.
Keywords: potential metabolic; profiling vaccine; vaccine development; metabolic profiling ... See more keywords