Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments
Sign Up to like & getrecommendations! Published in 2021 at "Nature immunology"
DOI: 10.1038/s41590-020-00848-3
Abstract: Metabolic programming controls immune cell lineages and functions, but little is known about γδ T cell metabolism. Here, we found that γδ T cell subsets making either interferon-γ (IFN-γ) or interleukin-17 (IL-17) have intrinsically distinct… read more here.
Keywords: programs established; cell subsets; established thymus; distinct metabolic ... See more keywords
Switching of metabolic programs in response to light availability is an essential function of the cyanobacterial circadian output pathway
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.23210
Abstract: The transcription factor RpaA is the master regulator of circadian transcription in cyanobacteria, driving genome-wide oscillations in mRNA abundance. Deletion of rpaA has no effect on viability in constant light conditions, but renders cells inviable… read more here.
Keywords: switching metabolic; programs response; output pathway; circadian output ... See more keywords