Melatonin, an ubiquitous metabolic regulator: functions, mechanisms and effects on circadian disruption and degenerative diseases
Sign Up to like & getrecommendations! Published in 2020 at "Reviews in Endocrine and Metabolic Disorders"
DOI: 10.1007/s11154-020-09570-9
Abstract: The last four decades, we assist to an increasing scientific interest on melatonin, a circadian hormone, a metabolic regulator which influences not only plants’ metabolism and their defense against pathogens but mostly the animals and… read more here.
Keywords: metabolic regulator; diseases melatonin; circadian disruption; degenerative diseases ... See more keywords
The Role of MPZL3 as a Metabolic Regulator in Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.10.280
Abstract: Ovarian cancer is comprised of multiple histological subtypes that vary widely in metabolic phenotypes. Moreover, metabolic flexibility is required to sustain survival in different tumor niches during metastatic progression in the peritoneal cavity. For example,… read more here.
Keywords: mpzl3 metabolic; metabolic regulator; ovarian cancer; cancer ... See more keywords
The metabolic regulator Lamtor5 suppresses inflammatory signaling via regulating mTOR-mediated TLR4 degradation
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-019-0281-6
Abstract: Comprehensive immune responses are essential for eliminating pathogens but must be tightly controlled to avoid sustained immune activation and potential tissue damage. The engagement of TLR4, a canonical pattern recognition receptor, has been proposed to… read more here.
Keywords: metabolic regulator; degradation; regulator lamtor5; inflammatory signaling ... See more keywords
BRCA1: An Endocrine and Metabolic Regulator
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.844575
Abstract: The breast and ovarian cancer susceptibility gene (BRCA1) is a tumor suppressor whose mutation has been associated with the development of breast, ovarian and, probably, other malignancies at young ages. The BRCA1 gene product participates… read more here.
Keywords: brca1; brca1 endocrine; breast ovarian; endocrine metabolic ... See more keywords
A Key Metabolic Regulator of Bone and Cartilage Health
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology and Metabolism"
DOI: 10.3803/enm.2022.1443
Abstract: Taurine, a cysteine-derived zwitterionic sulfonic acid, is a common ingredient in energy drinks and is naturally found in fish and other seafood. In humans, taurine is produced mainly in the liver, and it can also… read more here.
Keywords: health; bone; cartilage; key metabolic ... See more keywords