Choline ameliorates cardiac hypertrophy by regulating metabolic remodelling and UPRmt through SIRT3-AMPK pathway
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvy217
Abstract: AIMS Cardiac hypertrophy is characterized by a shift in metabolic substrate utilization, but the molecular events underlying the metabolic remodelling remain poorly understood. We explored metabolic remodelling and mitochondrial dysfunction in cardiac hypertrophy and investigated… read more here.
Keywords: choline; cardiac hypertrophy; metabolic remodelling; hypertrophy ... See more keywords
Metabolic Remodelling: An Accomplice for New Therapeutic Strategies to Fight Lung Cancer
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DOI: 10.3390/antiox8120603
Abstract: Metabolic remodelling is a hallmark of cancer, however little has been unravelled in its role in chemoresistance, which is a major hurdle to cancer control. Lung cancer is a leading cause of death by cancer,… read more here.
Keywords: therapeutic strategies; metabolic remodelling; new therapeutic; lung cancer ... See more keywords