RNA dynamics revealed by metabolic RNA labeling and biochemical nucleoside conversions
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DOI: 10.1038/nmeth.4608
Abstract: The combination of metabolic RNA labeling with biochemical nucleoside conversion now adds a broadly applicable temporal dimension to RNA sequencing. read more here.
Keywords: rna dynamics; metabolic rna; biochemical nucleoside; rna ... See more keywords
On the optimal design of metabolic RNA labeling experiments
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DOI: 10.1371/journal.pcbi.1007252
Abstract: Massively parallel RNA sequencing (RNA-seq) in combination with metabolic labeling has become the de facto standard approach to study alterations in RNA transcription, processing or decay. Regardless of advances in the experimental protocols and techniques,… read more here.
Keywords: metabolic rna; optimal design; rna labeling; design metabolic ... See more keywords