Potent Metabolic Sialylation Inhibitors Based on C-5-Modified Fluorinated Sialic Acids
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.8b01757
Abstract: Sialic acid sugars on mammalian cells regulate numerous biological processes, while aberrant expression of sialic acid is associated with diseases such as cancer and pathogenic infection. Inhibition of the sialic acid biosynthesis may therefore hold… read more here.
Keywords: sialylation inhibitors; potent metabolic; inhibitors based; metabolic sialylation ... See more keywords