Metabolic side effects induced by olanzapine treatment are neutralized by CB1 receptor antagonist compounds co-administration in female rats
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.03.010
Abstract: Weight gain is an important side effect of most atypical antipsychotic drugs such as olanzapine. Moreover, although many animal models with metabolic side effects have been well defined, the interaction with other pathways has to… read more here.
Keywords: metabolic side; treatment; weight gain; cb1 receptor ... See more keywords
Neuropsychiatric disorders: Side effects of olanzapine worsened by metabolic dysfunction
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Endocrinology"
DOI: 10.1038/nrendo.2017.183
Abstract: generation antipsychotic drug, can cause metabolic side effects, including hyperphagia, weight gain and acute hyperglycaemia. Previously, researchers used lean, healthy rodents to investigate the mechanisms behind olanzapine-associated acute hyperglycaemia; however, individuals with schizophrenia are often… read more here.
Keywords: insulin; metabolic side; hyperglycaemia; mice ... See more keywords