Partners with a killer: Metabolic signaling promotes inflammatory cell death
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.07.036
Abstract: In this issue of Cell, Evavold et al. (2021) report that mTOR Complex 1 (mTORC1), a metabolic signaling complex, controls reactive oxygen species (ROS) production in mitochondria, which in turn promotes inflammatory cell death mediated by… read more here.
Keywords: promotes inflammatory; inflammatory cell; cell death; cell ... See more keywords
Selenium nanoparticles for targeted stroke therapy through modulation of inflammatory and metabolic signaling
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-42633-9
Abstract: Ischemic cerebral stroke is a major cause of death and morbidity. Currently, no neuroprotective agents have been shown to impact the clinical outcomes in cerebral stroke cases. Here, we report therapeutic effects of Se nanoparticles… read more here.
Keywords: signaling pathways; nanoparticles targeted; inflammatory metabolic; cerebral stroke ... See more keywords
Metabolic Signaling and Spatial Interactions in the Oral Polymicrobial Community
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DOI: 10.1177/0022034519866440
Abstract: Oral supra- and subgingival biofilms are complex communities in which hundreds of bacteria, viruses, and fungi reside and interact. In these social environments, microbes compete and cooperate for resources, such as living space and nutrients.… read more here.
Keywords: community; signaling spatial; polymicrobial community; spatial interactions ... See more keywords
Roles of Bromodomain Extra Terminal Proteins in Metabolic Signaling and Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15081032
Abstract: BET proteins, which recognize and bind to acetylated histones, play a key role in transcriptional regulation. The development of chemical BET inhibitors in 2010 greatly facilitated the study of these proteins. BETs play crucial roles… read more here.
Keywords: bet; roles bromodomain; bromodomain extra; metabolic signaling ... See more keywords
Nucleoredoxin-like 2 metabolic signaling impairs its potential contribution to neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.346476
Abstract: COMMENTS TO AUTHORS The title of the article "Metabolic Signaling Impairment in the Progression of Alzheimer's Disease" might suggest a review manuscript, but the draft appears more like a prospective paper. In the introduction, the… read more here.
Keywords: like metabolic; impairs potential; nucleoredoxin like; metabolic signaling ... See more keywords