Untargeted metabolic analysis in dried blood spots reveals metabolic signature in 22q11.2 deletion syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Translational Psychiatry"
DOI: 10.1038/s41398-022-01859-4
Abstract: The 22q11.2 deletion syndrome (22q11.2DS) is characterized by a well-defined microdeletion and is associated with increased risk of neurodevelopmental phenotypes including autism spectrum disorders (ASD) and intellectual impairment. The typically deleted region in 22q11.2DS contains… read more here.
Keywords: analysis; 22q11 2ds; metabolic signature; 22q11 deletion ... See more keywords
The Mediterranean diet, plasma metabolome, and cardiovascular disease risk.
Sign Up to like & getrecommendations! Published in 2020 at "European heart journal"
DOI: 10.1093/eurheartj/ehaa209
Abstract: AIMS To investigate whether metabolic signature composed of multiple plasma metabolites can be used to characterize adherence and metabolic response to the Mediterranean diet and whether such a metabolic signature is associated with cardiovascular disease… read more here.
Keywords: risk; disease; metabolic signature; signature ... See more keywords
The metabolic signature of T cells in rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000683
Abstract: PURPOSE OF REVIEW Rheumatoid arthritis (RA) is a prototypic autoimmune disease manifesting as chronic inflammation of the synovium and leading to acceleration of cardiovascular disease and shortening of life expectancy. The basic defect causing autoimmunity… read more here.
Keywords: rheumatoid arthritis; signature cells; cell; metabolic signature ... See more keywords
A metabolism-relevant signature as a predictor for prognosis and therapeutic response in pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental biology and medicine"
DOI: 10.1177/15353702211049220
Abstract: Although several altered metabolic genes have been identified to be involved in the tumorigenesis and advance of pancreatic cancer (PC), their prognostic values remained unclear. The purpose of this study was to explore new targets… read more here.
Keywords: response; metabolism; pancreatic cancer; metabolic signature ... See more keywords
The Metabolic Signature of Macrophage Responses
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01462
Abstract: Macrophages are a heterogeneous population of immune cells playing several and diverse functions in homeostatic and immune responses. The broad spectrum of macrophage functions depends on both heterogeneity and plasticity of these cells, which are… read more here.
Keywords: anti inflammatory; metabolism; metabolic signature; macrophage ... See more keywords
Searching for the Metabolic Signature of Cancer: A Review from Warburg’s Time to Now
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101412
Abstract: This review focuses on the evolving understanding that we have of tumor cell metabolism, particularly glycolytic and oxidative metabolism, and traces back its evolution through time. This understanding has developed since the pioneering work of… read more here.
Keywords: time; review; signature cancer; cancer ... See more keywords
A Metabolic Signature of Hereditary Transthyretin Amyloidosis: A Pilot Study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232416133
Abstract: Hereditary transthyretin amyloidosis is the most common form of hereditary amyloidosis, with an autosomal dominant inheritance and a variable penetrance. ATTRv amyloidosis can present as a progressive, axonal sensory autonomic and motor neuropathy or as… read more here.
Keywords: amyloidosis; hereditary transthyretin; transthyretin amyloidosis; study ... See more keywords
Untargeted Metabolomics Analysis of the Serum Metabolic Signature of Childhood Obesity
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14010214
Abstract: Obesity rates among children are growing rapidly worldwide, placing massive pressure on healthcare systems. Untargeted metabolomics can expand our understanding of the pathogenesis of obesity and elucidate mechanisms related to its symptoms. However, the metabolic… read more here.
Keywords: untargeted metabolomics; childhood; signature childhood; obesity ... See more keywords