Metabolic signatures of regulation by phosphorylation and acetylation
Sign Up to like & getrecommendations! Published in 2022 at "iScience"
DOI: 10.1016/j.isci.2021.103730
Abstract: Summary Acetylation and phosphorylation are highly conserved posttranslational modifications (PTMs) that regulate cellular metabolism, yet how metabolic control is shared between these PTMs is unknown. Here we analyze transcriptome, proteome, acetylome, and phosphoproteome datasets in… read more here.
Keywords: phosphorylation acetylation; metabolic signatures; machine learning; acetylation ... See more keywords
Urine Metabolic Signatures of Multiple Environmental Pollutants in Pregnant Women: An Exposome Approach.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental science & technology"
DOI: 10.1021/acs.est.8b02215
Abstract: Exposure to environmental pollutants, particularly during pregnancy, can have adverse consequences on child development but little is known about the effects of pollutant mixtures on endogenous metabolism in pregnant women. We aimed to identify urinary… read more here.
Keywords: environmental pollutants; multiple environmental; pregnant women; exposure ... See more keywords
Dietary metabolic signatures and cardiometabolic risk.
Sign Up to like & getrecommendations! Published in 2022 at "European heart journal"
DOI: 10.1093/eurheartj/ehac446
Abstract: AIMS Observational studies of diet in cardiometabolic-cardiovascular disease (CM-CVD) focus on self-reported consumption of food or dietary pattern, with limited information on individual metabolic responses to dietary intake linked to CM-CVD. Here, machine learning approaches… read more here.
Keywords: long term; food; risk; cvd ... See more keywords
Transcriptomic and metabolic signatures of diatom plasticity to light fluctuations.
Sign Up to like & getrecommendations! Published in 2022 at "Plant physiology"
DOI: 10.1093/plphys/kiac455
Abstract: Unlike in terrestrial and freshwater ecosystems, light fields in oceans fluctuate due to both horizontal current and vertical mixing. Diatoms thrive and dominate the phytoplankton community in these fluctuating light fields. However, the molecular mechanisms… read more here.
Keywords: light fluctuations; light fluctuation; transcriptomic metabolic; light ... See more keywords
Metabolic Signatures from Genebank Collections: An Underexploited Resource for Human Health?
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of food science and technology"
DOI: 10.1146/annurev-food-060822-113022
Abstract: Despite the almost universal acceptance of the phrase "you are what you eat," investment in understanding diet-based nutrition to address human health has been dwarfed compared to that for medicine-based interventions. Moreover, traditional breeding has… read more here.
Keywords: collections underexploited; health; human health; signatures genebank ... See more keywords
Plasma metabolomics study reveals the critical metabolic signatures for benzene-induced hematotoxicity
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.154999
Abstract: Metabolomics has been used to explore the molecular mechanism and screen biomarkers. However, the critical metabolic signatures associated with benzene-induced hematotoxicity remain elusive. Here, we performed a plasma metabolomics study in 86 benzene-exposed workers and… read more here.
Keywords: benzene induced; critical metabolic; induced hematotoxicity; metabolic signatures ... See more keywords
Genetic and metabolic signatures of Salmonella enterica subsp. enterica associated with animal sources at the pangenomic scale
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-6188-x
Abstract: BackgroundSalmonella enterica subsp. enterica is a public health issue related to food safety, and its adaptation to animal sources remains poorly described at the pangenome scale. Firstly, serovars presenting potential mono- and multi-animal sources were selected… read more here.
Keywords: subsp enterica; associated animal; genetic metabolic; enterica subsp ... See more keywords
Fish Macrophages Show Distinct Metabolic Signatures Upon Polarization
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00152
Abstract: Macrophages play important roles in conditions ranging from host immune defense to tissue regeneration and polarize their functional phenotype accordingly. Next to differences in the use of L-arginine and the production of different cytokines, inflammatory… read more here.
Keywords: show distinct; metabolic reprogramming; distinct metabolic; metabolic signatures ... See more keywords
Salivary metabolic signatures of carotid atherosclerosis in patients with type 2 diabetes hospitalized for treatment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1074285
Abstract: Atherosclerosis is a life-threatening disease associated with morbidity and mortality in patients with type 2 diabetes (T2D). This study aimed to characterize a salivary signature of atherosclerosis based on evaluation of carotid intima-media thickness (IMT)… read more here.
Keywords: patients type; atherosclerosis; type diabetes; salivary metabolic ... See more keywords
Exosomal Metabolic Signatures Are Associated with Differential Response to Neoadjuvant Chemotherapy in Patients with Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23105324
Abstract: Neoadjuvant chemotherapy (NAC) is commonly used in breast cancer (BC) patients to increase eligibility for breast-conserving surgery. Only 30% of patients with BC show pathologic complete response (pCR) after NAC, and residual disease (RD) is… read more here.
Keywords: neoadjuvant chemotherapy; signatures associated; exosomal metabolic; breast cancer ... See more keywords