Impact of Drug Conjugation on Thermal and Metabolic Stabilities of Aglycosylated and N-Glycosylated Antibodies
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DOI: 10.1021/acs.bioconjchem.1c00572
Abstract: N-linked glycosylation is one of the most common and complex posttranslational modifications that govern the biological functions and physicochemical properties of therapeutic antibodies. We evaluated thermal and metabolic stabilities of antibody–drug conjugates (ADCs) with payloads… read more here.
Keywords: drug conjugation; impact drug; conjugation; thermal metabolic ... See more keywords