The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons
Sign Up to like & getrecommendations! Published in 2019 at "Immunity"
DOI: 10.1016/j.immuni.2018.11.017
Abstract: Summary As long‐lived post‐mitotic cells, neurons employ unique strategies to resist pathogen infection while preserving cellular function. Here, using a murine model of Zika virus (ZIKV) infection, we identified an innate immune pathway that restricts… read more here.
Keywords: death; infection; state neurons; metabolic state ... See more keywords
Met-Flow, a strategy for single-cell metabolic analysis highlights dynamic changes in immune subpopulations
Sign Up to like & getrecommendations! Published in 2020 at "Communications Biology"
DOI: 10.1038/s42003-020-1027-9
Abstract: A complex interaction of anabolic and catabolic metabolism underpins the ability of leukocytes to mount an immune response. Their capacity to respond to changing environments by metabolic reprogramming is crucial to effector function. However, current… read more here.
Keywords: single cell; flow strategy; metabolic state; cell ... See more keywords
Nutritional status, metabolic state and nutrient intake in children with bronchiolitis
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Food Sciences and Nutrition"
DOI: 10.1080/09637486.2016.1245714
Abstract: Abstract Nutrition has a coadjuvant role in the management of children with acute diseases. We aimed to examine nutritional status, macronutrient requirements and actual macronutrient delivery in bronchiolitis. The nutritional status was classified according to… read more here.
Keywords: status; status metabolic; nutritional status; metabolic state ... See more keywords
Metabolic state switches between morning and evening in association with circadian clock in non-diabetic humans.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of diabetes investigation"
DOI: 10.1111/jdi.13810
Abstract: AIMES/INTRODUCTION Understanding morning-evening variation in metabolic state is critical for managing metabolic disorders. We aimed to characterize this variation from the viewpoints of insulin secretion and insulin sensitivity, including their relevance to the circadian rhythm.… read more here.
Keywords: insulin; morning evening; morning; clock ... See more keywords
Analysis of the Metabolic State of Residual Multiple Myeloma Plasma Cells Reveals a Proliferative Subset with Glycolytic Gene Expression
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood.v130.suppl_1.4392.4392
Abstract: Most residual MMPCs have lower ROS and higher superoxide and mitochondrial content. A subset of residual cases had higher ROS levels along with elevated Myc, HK2, CD147 and reduced POU2F1 expression, possibly indicating… read more here.
Keywords: analysis metabolic; residual multiple; multiple myeloma; metabolic state ... See more keywords