Metabolic Tumor Imaging with Rapidly Signal‐Enhanced 1‐13C‐Pyruvate‐d3
Sign Up to like & getrecommendations! Published in 2022 at "Chemphyschem"
DOI: 10.1002/cphc.202200615
Abstract: Abstract The metabolism of malignant cells differs significantly from that of healthy cells and thus, it is possible to perform metabolic imaging to reveal not only the exact location of a tumor, but also intratumoral… read more here.
Keywords: signal enhanced; pyruvate; metabolic tumor; 13c pyruvate ... See more keywords
Metabolic tumor burden on baseline 18F-FDG PET/CT improves risk stratification in pediatric patients with mature B-cell lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04363-y
Abstract: PurposeIn order to better identify patients most at risk of treatment failure and disease progression in pediatric mature B-cell non-Hodgkin lymphoma (B-NHL), the prognostic role of metabolic tumor burden measured on baseline 18F-FDG PET/CT scan,… read more here.
Keywords: fdg pet; tlg; metabolic tumor; 18f fdg ... See more keywords
18F-FDG PET/CT metabolic tumor parameters and radiomics features in aggressive non-Hodgkin’s lymphoma as predictors of treatment outcome and survival
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Nuclear Medicine"
DOI: 10.1007/s12149-018-1260-1
Abstract: PurposeTo determine whether metabolic tumor parameters and radiomic features extracted from 18F-FDG PET/CT (PET) can predict response to therapy and outcome in patients with aggressive B-cell lymphoma.MethodsThis institutional ethics board-approved retrospective study included 82 patients… read more here.
Keywords: response; tumor parameters; metabolic tumor; therapy ... See more keywords
Clinical implications of circulating cell-free DNA quantification and metabolic tumor burden in advanced non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Lung cancer"
DOI: 10.1016/j.lungcan.2019.06.014
Abstract: OBJECTIVES This study unravels the significance of cell-free DNA (cfDNA) quantification as a promising measure of the biological behavior/aggressiveness of tumors. Metabolic tumor volume (MTV) and total lesion glycolysis (TLG) measured by positron emission tomography/computed… read more here.
Keywords: cfdna; tumor burden; cell; cfdna levels ... See more keywords
Combination of Circulating Cell-Free DNA and Positron Emission Tomography to Distinguish Non-Small Cell Lung Cancer from Tuberculosis.
Sign Up to like & getrecommendations! Published in 2022 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac085
Abstract: OBJECTIVE Non-small cell lung cancer (NSCLC) holds high metabolic tumor burden and circulating cell-free DNA (cfDNA) levels, and the relationship between metabolic tumor burden and cfDNA in NSCLC and the underlying mechanism of their interaction… read more here.
Keywords: tuberculosis; tumor burden; cell; metabolic tumor ... See more keywords
High total metabolic tumor volume at baseline allows discrimination of survival even in patients aged 60 to 80 years responding to R-CHOP.
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood.2019003526
Abstract: Early identification of ultra-risk diffuse large B-cell lymphoma (DLBCL) patients is needed to aid stratification to innovative treatment. Previous studies suggested high baseline total metabolic tumor volume (TMTV) negatively impacts survival of DLBCL patients. We… read more here.
Keywords: total metabolic; pfs; tmtv; baseline ... See more keywords
Baseline cell-free DNA (cfDNA) and metabolic tumor volume (MTV) independently predict outcome in metastatic chemorefractory colorectal cancer (mCRC).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.11569
Abstract: 11569Background: No validated prognostic biomarker is currently available for mCRC. This trial assessed cfDNA and MTV before treatment with regorafenib as prognostic biomarkers for progression-free... read more here.
Keywords: dna cfdna; baseline cell; free dna; cfdna metabolic ... See more keywords
PET metabolic tumor volume as a new prognostic factor in childhood rhabdomyosarcoma
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DOI: 10.1371/journal.pone.0261565
Abstract: Purpose Childhood RMS is a rare malignant disease in which evaluation of tumour spread at diagnosis is essential for therapeutic management. F-18 FDG-PET imaging is currently used for initial RMS disease staging. Materials and methods… read more here.
Keywords: suvpeak bone; childhood; metabolic tumor; bone lysis ... See more keywords
Repeatability of metabolic tumor burden and lesion glycolysis between clinical readers
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.994520
Abstract: The Metabolic Tumor Volume (MTV) and Tumor Lesion Glycolysis (TLG) has been shown to be independent prognostic predictors for clinical outcome in Diffuse Large B-cell Lymphoma (DLBCL). However, definitions of these measurements have not been… read more here.
Keywords: metabolic tumor; reader; lesion; lesion glycolysis ... See more keywords
Lymphoma tumor burden before chimeric antigen receptor T-Cell treatment: RECIL vs. Lugano vs. metabolic tumor assessment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.974029
Abstract: Purpose High tumor burden has emerged as a negative predictor of efficacy in chimeric antigen receptor T-cell therapy (CART) in patients with refractory or relapsed large B-cell lymphoma. This study analyzed the deviation among imaging-based… read more here.
Keywords: cell; assessment; metabolic tumor; tumor burden ... See more keywords
A Deep Learning-Aided Automated Method for Calculating Metabolic Tumor Volume in Diffuse Large B-Cell Lymphoma
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DOI: 10.3390/cancers14215221
Abstract: Simple Summary In recent years metabolic tumor volume (MTV) has been shown to predict outcomes in lymphoma. However, the current methods used to measure MTV are time-consuming and require manual input from the nuclear medicine… read more here.
Keywords: automated method; metabolic tumor; tumor volume; diffuse large ... See more keywords