Articles with "metabolism" as a keyword



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Mitochondria, energy, and metabolism in neuronal health and disease

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Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14298

Abstract: Mitochondria are associated with various cellular activities critical to homeostasis, particularly in the nervous system. The plastic architecture of the mitochondrial network and its dynamic structure play crucial roles in ensuring that varying energetic demands… read more here.

Keywords: metabolism; energy metabolism; mitochondria energy; energy ... See more keywords
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Nicotinamide adenine dinucleotide metabolism: driving or counterbalancing inflammatory bowel disease?

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Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14528

Abstract: Nicotinamide adenine dinucleotide (NAD) is an important electron and hydrogen carrier for oxidative metabolism and involved in energy production, antioxidant responses, and signal transduction within cells. NAD‐consuming enzymes can mediate post‐translational modifications, such as deacylation… read more here.

Keywords: metabolism; nicotinamide adenine; adenine dinucleotide; inflammatory bowel ... See more keywords
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Nicotinamide (niacin) supplement increases lipid metabolism and ROS‐induced energy disruption in triple‐negative breast cancer: potential for drug repositioning as an anti‐tumor agent

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Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13209

Abstract: Metabolic dysregulation is an important hallmark of cancer. Nicotinamide (NAM), a water‐soluble amide form of niacin (vitamin B3), is currently available as a supplement for maintaining general physiologic functions. NAM is a crucial regulator of… read more here.

Keywords: metabolism; supplement; triple negative; ros ... See more keywords
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Sphingosine‐1‐phosphate‐lyase deficiency affects glucose metabolism in a way that abets oncogenesis

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Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13300

Abstract: Sphingosine‐1‐phosphate (S1P), a bioactive signaling lipid, is involved in several vital processes, including cellular proliferation, survival and migration, as well as neovascularization and inflammation. Its critical role in the development and progression of cancer is… read more here.

Keywords: metabolism; s1p; glucose metabolism; lyase ... See more keywords
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Metabolism in the tumour cell and beyond.

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Published in 2023 at "Molecular oncology"

DOI: 10.1002/1878-0261.13467

Abstract: The process of cellular transformation encompasses the acquisition of key and distinctive features, commonly known as hallmarks of cancer. These hallmarks are supported by tumour-intrinsic molecular alterations as well as changes in the microenvironment. Cellular… read more here.

Keywords: metabolism; tumour cell; metabolism tumour; biology ... See more keywords
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Understanding feedbacks between ocean acidification and coral reef metabolism

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Published in 2017 at "Journal of Geophysical Research"

DOI: 10.1002/2017jc012740

Abstract: Biogeochemical feedbacks from benthic metabolism have been hypothesized as a potential mechanism to buffer some effects of ocean acidification on coral reefs. The article in JGR-Oceans by DeCarlo et al. demonstrates the importance of benthic… read more here.

Keywords: understanding feedbacks; metabolism; ocean acidification; feedbacks ocean ... See more keywords
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Hypoxia exposure alleviates impaired muscular metabolism, glucose tolerance, and aerobic capacity in apelin‐knockout mice

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Published in 2019 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12587

Abstract: High altitude hypoxia adaptation can improve glucose tolerance in people with metabolic syndrome and type 2 diabetes (T2D). Apelin is an endogenous ligand of the G protein‐coupled receptor APJ and has possible roles in energy… read more here.

Keywords: hypoxia; metabolism; hypoxia exposure; mice ... See more keywords
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Tumor Metabolism‐Engineered Composite Nanoplatforms Potentiate Sonodynamic Therapy via Reshaping Tumor Microenvironment and Facilitating Electron–Hole Pairs’ Separation

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Published in 2020 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202000326

Abstract: Reactive oxygen species (ROS) depletion and low ROS production that result from the intratumoral redox metabolism equilibrium and low energy conversion efficiency from ultrasound mechanical energy to ROS‐represented chemical energy, respectively, are two vital inhibitory… read more here.

Keywords: tumor; metabolism engineered; tumor metabolism; separation ... See more keywords
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Glutamine‐Based Metabolism Normalization and Oxidative Stress Alleviation by Self‐Assembled Bilirubin/V9302 Nanoparticles for Psoriasis Treatment

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Published in 2023 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202203397

Abstract: Psoriasis is an immune‐mediated chronic inflammatory skin disorder characterized by epidermal hyperplasia and infiltration of inflammatory cells. Even though the pathogenesis remains unclear, T helper 17 (Th17) cells‐mediated inflammation and keratinocyte‐involved proliferation are considered to… read more here.

Keywords: metabolism; oxidative stress; self; psoriasis ... See more keywords
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Nanozyme-Based Regulation of Cellular Metabolism and their Applications.

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Published in 2023 at "Advanced materials"

DOI: 10.1002/adma.202301810

Abstract: Metabolism is the sum of the enzyme-dependent chemical reactions, which produces energy in catabolic process and synthesizes biomass in anabolic process, exhibiting high similarity in mammalian cell, microbial cell, and plant cell. Consequently, the loss… read more here.

Keywords: regulation cellular; metabolism; cell; nanozyme based ... See more keywords
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Biomimetic Nanocarriers Guide Extracellular ATP Homeostasis to Remodel Energy Metabolism for Activating Innate and Adaptive Immunity System

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Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202105376

Abstract: Metabolic interventions via targeting intratumoral dysregulated metabolism pathways have shown promise in reinvigorating antitumor immunity. However, approved small molecule immunomodulators often suffer from ineffective response rates and severe off‐target toxicity. ATP occupies a crucial role… read more here.

Keywords: metabolism; energy metabolism; immunity; tumor ... See more keywords