Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells
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DOI: 10.1038/s41598-020-68396-2
Abstract: Inspired by recent proteomic data demonstrating the upregulation of carbon and glycogen metabolism in aging human hematopoietic stem and progenitor cells (HPCs, CD34+ cells), this report addresses whether this is caused by elevated glycolysis of… read more here.
Keywords: progenitor cells; carbon; stem progenitor; hematopoietic stem ... See more keywords
TOR‐mediated regulation of metabolism in aging
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DOI: 10.1111/acel.12689
Abstract: Cellular metabolism is regulated by the mTOR kinase, a key component of the molecular nutrient sensor pathway that plays a central role in cellular survival and aging. The mTOR pathway promotes protein and lipid synthesis… read more here.
Keywords: regulation metabolism; mediated regulation; tor mediated; metabolism ... See more keywords
Iron Metabolism in Aging and Age-Related Diseases
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DOI: 10.3390/ijms23073612
Abstract: Iron is a trace metal element necessary to maintain life and is also involved in a variety of biological processes. Aging refers to the natural life process in which the physiological functions of the various… read more here.
Keywords: metabolism aging; iron metabolism; iron; age related ... See more keywords