Lipid Metabolism Disorder and Renal Fibrosis.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8871-2_26
Abstract: Since the lipid nephrotoxicity hypothesis was proposed in 1982, increasing evidence has supported the hypothesis that lipid abnormalities contributed to the progression of glomerulosclerosis. In this chapter, we will discuss the general promises of the… read more here.
Keywords: fibrosis; disorder renal; renal fibrosis; metabolism disorder ... See more keywords
Selenium alleviates mercury chloride-induced liver injury by regulating mitochondrial dynamics to inhibit the crosstalk between energy metabolism disorder and NF-κB/NLRP3 inflammasome-mediated inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2021.113018
Abstract: Mercury (Hg) is a persistent heavy metal contaminant with definite hepatotoxicity. Selenium (Se) has been shown to alleviate liver damage induced by heavy metals. Therefore, the present study aimed to explore the mechanism of the… read more here.
Keywords: liver injury; metabolism; inflammation; metabolism disorder ... See more keywords
Untargeted Lipidomics Revealed the Protective Effects of Cyanidin-3-O-glucoside on Bisphenol A-Induced Liver Lipid Metabolism Disorder in Rats.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c06849
Abstract: Bisphenol A (BPA) is an estrogenic endocrine disruptor that induces metabolic disorders. Cyanidin-3-O-glucoside (C3G) has multiple functional activities and is the most abundant anthocyanin belonging to the flavonoid subgroup. This study aimed to investigate the… read more here.
Keywords: metabolism; metabolism disorder; lipid metabolism; cyanidin glucoside ... See more keywords
Crotonaldehyde exposure induces liver dysfunction and mitochondrial energy metabolism disorder in rats
Sign Up to like & getrecommendations! Published in 2021 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2021.1904073
Abstract: Abstract Crotonaldehyde is a highly toxic pollutant, widely present in tobacco smoke and automobile exhaust. Exposure to crotonaldehyde can cause hepatotoxicity and induce liver tumors in rats; however, the underlying mechanism is unclear. Liver cells… read more here.
Keywords: energy; exposure; metabolism disorder; crotonaldehyde exposure ... See more keywords
Farnesoid X Receptor Deficiency Induces Hepatic Lipid and Glucose Metabolism Disorder via Regulation of Pyruvate Dehydrogenase Kinase 4
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/3589525
Abstract: Farnesoid X receptors (FXR) are bile acid receptors that play roles in lipid, glucose, and energy homeostasis. Synthetic FXR-specific agonists have been developed for treating nonalcoholic fatty liver disease (NAFLD) patients. However, the detailed mechanism… read more here.
Keywords: dehydrogenase kinase; metabolism disorder; pyruvate dehydrogenase; glucose metabolism ... See more keywords
The Molecular Mechanism of Hepatic Lipid Metabolism Disorder Caused by NaAsO2 through Regulating the ERK/PPAR Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/6405911
Abstract: Chronic arsenic exposure is a risk factor for human fatty liver disease, and the ERK signaling pathway plays an important role in the regulation of liver lipid metabolism. However, whether ERK plays a role in… read more here.
Keywords: metabolism disorder; lipid metabolism; erk; ppar ... See more keywords
Evaluation of patients with phenylalanine metabolism disorder: a single center experience
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pediatric Endocrinology and Metabolism"
DOI: 10.1515/jpem-2021-0737
Abstract: Abstract Aim The aim is to evaluate the clinical, demographic and laboratory data of the patients we followed up with phenylalanine metabolism disorder. Materials and methods In this study, patients with phenylalanine metabolism disorder who… read more here.
Keywords: group; metabolism disorder; metabolism; phenylalanine metabolism ... See more keywords
Occurrence of Chordoid Glioma With Sodium Ion Metabolism Disorder 5 Years After Meningioma Surgery and Whole-Exome Sequencing: A Case Report and Literature Review
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.617575
Abstract: Chordoid glioma (CG), a rare slow-growing brain tumor, mainly occurs in the region of the third ventricle. Although its degree of malignancy is relatively low, its clinical prognosis is poor due to obscure clinical manifestations… read more here.
Keywords: sodium ion; chordoid glioma; ion metabolism; ion ... See more keywords
Integrating Constituents Absorbed into Blood, Network Pharmacology, and Quantitative Analysis to Reveal the Active Components in Rubus chingii var. suavissimus that Regulate Lipid Metabolism Disorder
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.630198
Abstract: Rubus chingii var. suavissimus (S. K. Lee) L. T. Lu (RS)—a sweet plant also known as Tiancha distributed in the south of China where it is used as a beverage—recently gained extensive attention as adjuvant… read more here.
Keywords: rubus chingii; chingii var; pharmacology; metabolism disorder ... See more keywords
The mechanisms of glycolipid metabolism disorder on vascular injury in type 2 diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.952445
Abstract: Patients with diabetes have severe vascular complications, such as diabetic nephropathy, diabetic retinopathy, cardiovascular disease, and neuropathy. Devastating vascular complications lead to increased mortality, blindness, kidney failure, and decreased overall quality of life in people… read more here.
Keywords: vascular injury; vascular complications; metabolism disorder; type diabetes ... See more keywords