In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer’s Disease, Major Depressive Disorder, and Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-018-1035-0
Abstract: Ammonia is a toxic by-product of protein catabolism and is involved in changes in glutamate metabolism. Therefore, ammonia metabolism genes may link a range of diseases involving glutamate signaling such as Alzheimer’s disease (AD), major… read more here.
Keywords: snps; glul; metabolism genes; cps1 ... See more keywords
Adaptation mechanisms of arsenic metabolism genes and their host microorganisms in soils with different arsenic contamination levels around abandoned gold tailings.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.117994
Abstract: Soil around the gold tailing due to the smelting process of wastewater and solid waste can lead to metal (loids) contamination, especially arsenic (As). Soil microorganisms have gradually evolved adaptive mechanisms in the process of… read more here.
Keywords: host microorganisms; genes host; metabolism; metabolism genes ... See more keywords
Copy number variants in lipid metabolism genes are associated with gallstones disease in men
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-019-0501-7
Abstract: Gallstones Disease (GSD) is one of the most common digestive diseases requiring hospitalization and surgical procedures in the world. GSD has a high prevalence in populations with European or Amerindian ancestry (10–20%) and the influence… read more here.
Keywords: copy number; metabolism; metabolism genes; number variants ... See more keywords
Breast cancer combined prognostic model based on lactate metabolism genes
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000032485
Abstract: To investigate the impact of lactate metabolism genes, lactate metabolism-related genes (LMRG), and immune infiltrating cells on the prognosis of breast cancer. LMRG was identified via single-cell sequencing. Immune cell infiltration was obtained by the… read more here.
Keywords: metabolism; lactate metabolism; metabolism genes; breast cancer ... See more keywords
The galactose metabolism genes UGE1 and UGM1 are novel virulence factors of the maize anthracnose fungus Colletotrichum graminicola
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Microbiology"
DOI: 10.1111/mmi.15242
Abstract: Fungal cell walls represent the frontline contact with the host and play a prime role in pathogenesis. While the roles of the cell wall polymers like chitin and branched β‐glucan are well understood in vegetative… read more here.
Keywords: colletotrichum graminicola; type galactomannan; fungal type; uge1 ugm1 ... See more keywords
Transcriptomic profiling of hepatic tissues for drug metabolism genes in nonalcoholic fatty liver disease: A study of human and animals
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1034494
Abstract: Background Drug metabolism genes are involved in the in vivo metabolic processing of drugs. In previous research, we found that a high-fat diet affected the transcript levels of mouse hepatic genes responsible for drug metabolism.… read more here.
Keywords: nonalcoholic fatty; fatty liver; metabolism genes; drug metabolism ... See more keywords
Machine learning to construct sphingolipid metabolism genes signature to characterize the immune landscape and prognosis of patients with uveal melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1056310
Abstract: Background Uveal melanoma (UVM) is the most common primary intraocular malignancy in adults and is highly metastatic, resulting in a poor patient prognosis. Sphingolipid metabolism plays an important role in tumor development, diagnosis, and prognosis.… read more here.
Keywords: sphingolipid metabolism; prognosis; metabolism genes; risk ... See more keywords
Identification of subtypes of clear cell renal cell carcinoma and construction of a prognostic model based on fatty acid metabolism genes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1013178
Abstract: Background: The effects of fatty acid metabolism in many tumors have been widely reported. Due to the diversity of lipid synthesis, uptake, and transformation in clear cell renal cell carcinoma (ccRCC) cells, many studies have… read more here.
Keywords: cell; prognosis; acid metabolism; metabolism genes ... See more keywords
Genetic Variants of Glycogen Metabolism Genes Were Associated With Liver PDFF Without Increasing NAFLD Risk
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.830445
Abstract: Background/Aims: The storage amount of liver glycogen could affect the liver fibrosis assessment made by MRI-based methods. However, it remained unclear whether glycogen amount could bias the estimation of liver fat content by proton density… read more here.
Keywords: genes associated; glycogen metabolism; glycogen; metabolism genes ... See more keywords
Identification of Key Nucleotide Metabolism Genes in Diabetic Retinopathy Based on Bioinformatics Analysis and Experimental Verification
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DOI: 10.3390/biology14040409
Abstract: Simple Summary The mechanisms involved in nucleotide metabolism in DR were investigated based on RNA sequencing data and single-cell data in diabetic retinopathy (DR). The results demonstrate that HMOX1, TLR4, and ACE are core genes… read more here.
Keywords: metabolism genes; nucleotide metabolism; diabetic retinopathy; key nucleotide ... See more keywords
The Carbohydrate Metabolism of Lactiplantibacillus plantarum
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222413452
Abstract: Lactiplantibacillus plantarum has a strong carbohydrate utilization ability. This characteristic plays an important role in its gastrointestinal tract colonization and probiotic effects. L. plantarum LP-F1 presents a high carbohydrate utilization capacity. The genome analysis of… read more here.
Keywords: carbohydrate metabolism; sugar metabolism; metabolism lactiplantibacillus; metabolism genes ... See more keywords