Multiomics-based energy metabolism heterogeneity and its regulation by antiparasite drug ivermectin.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e18080
Abstract: e18080Background: Energy metabolism heterogeneity is a hallmark in ovarian cancer, namely the Warburg effect and the reverse Warburg effects coexist in ovarian cancer. Exploration of energy metabol... read more here.
Keywords: metabolism heterogeneity; energy metabolism; multiomics based; energy ... See more keywords
Metabolism heterogeneity in melanoma fuels deactivation of immunotherapy: Predict before protect
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1046102
Abstract: Malignant melanoma is widely acknowledged as the most lethal skin malignancy. The metabolic reprogramming in melanoma leads to alterations in glycolysis and oxidative phosphorylation (OXPHOS), forming a hypoxic, glucose-deficient and acidic tumor microenvironment which inhibits… read more here.
Keywords: metabolism; melanoma; immunotherapy; tumor microenvironment ... See more keywords