Untargeted metabolomics reveals alterations in metabolites of lipid metabolism and immune pathways in the serum of rats after long-term oral administration of Amalaki rasayana
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03637-1
Abstract: Amalaki rasayana, a traditional preparation, is widely used by Ayurvedic physicians for the treatment of inflammatory conditions, cardiovascular diseases, and cancer. Metabolic alterations induced by Amalaki rasayana intervention are unknown. We investigated the modulations in… read more here.
Keywords: amalaki rasayana; metabolism; metabolism immune; long term ... See more keywords
Reprogramming of metabolism in immune-mediated cells
Sign Up to like & getrecommendations! Published in 2017 at "Diabetology International"
DOI: 10.1007/s13340-017-0321-3
Abstract: The development of a sensitive assay using an extracellular flux analyzer has enabled the determination of lactate, the end product of glycolysis, by measuring the pH (extracellular acidification rate; ECAR) of living cells, such as… read more here.
Keywords: reprogramming metabolism; mediated cells; metabolism immune; pmol mph ... See more keywords
Modeling the energy metabolism in immune cells.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2021.03.003
Abstract: In this review, we summarize and briefly discuss various approaches to modeling the metabolism in human immune cells, with a focus on energy metabolism. These approaches include metabolic reconstruction, elementary modes, and flux balance analysis,… read more here.
Keywords: metabolism; modeling energy; metabolism immune; immune cells ... See more keywords
Molecular regulations of metabolism during immune response in insects.
Sign Up to like & getrecommendations! Published in 2019 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2019.04.005
Abstract: Mounting an immune response is an energy-consuming process. Activating immune functions requires the synthesis of many new molecules and the undertaking of numerous cellular tasks and it must happen rapidly. Therefore, immune cells undergo a… read more here.
Keywords: insects; response; energy; metabolism immune ... See more keywords
Tryptophan metabolism and immune regulation in the human placenta.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2021.103361
Abstract: The placenta represents the maternal-fetal vascular interface. It is capable of supplying the bioenergetic needs of the developing conceptus. It is composed of different cell types that engage in highly varied functions, ranging from attachment,… read more here.
Keywords: tryptophan; placenta; metabolism immune; tryptophan metabolism ... See more keywords
Leptin in the interplay of inflammation, metabolism and immune system disorders
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DOI: 10.1038/nrrheum.2016.209
Abstract: Leptin is one of the most relevant factors secreted by adipose tissue and the forerunner of a class of molecules collectively called adipokines. Initially discovered in 1994, its crucial role as a central regulator in… read more here.
Keywords: metabolism; leptin; inflammation; metabolism immune ... See more keywords
Glycosylation modification patterns reveal distinct tumor metabolism and immune microenvironment landscape in lower-grade gliomas
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.886989
Abstract: Glycosylation alterations, a key driver throughout tumorigenesis and tumor progression, could regulate the microenvironment and immune response as well as lead to harmful metabolism and cell signaling. In this study, we first comprehensively evaluated the… read more here.
Keywords: modification; metabolism immune; glycosylation modification; glycosylation ... See more keywords
Iron Metabolism and Immune Regulation
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DOI: 10.3389/fimmu.2022.816282
Abstract: Iron is a critical element for living cells in terrestrial life. Although iron metabolism is strictly controlled in the body, disturbance of iron homeostasis under certain type of condition leads to innate and adaptive immune… read more here.
Keywords: iron metabolism; iron; metabolism immune; immune regulation ... See more keywords
Comprehensive analysis of a novel signature incorporating lipid metabolism and immune-related genes for assessing prognosis and immune landscape in lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.950001
Abstract: Background As the crosstalk between metabolism and antitumor immunity continues to be unraveled, we aim to develop a prognostic gene signature that integrates lipid metabolism and immune features for patients with lung adenocarcinoma (LUAD). Methods… read more here.
Keywords: metabolism immune; signature; lipid metabolism; analysis ... See more keywords
Rhamnolipids Regulate Lipid Metabolism, Immune Response, and Gut Microbiota in Rats
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DOI: 10.3389/fnut.2022.886256
Abstract: Objectives Gut microbes influence lipid metabolism and immune responses that are key features of metabolic disorders. This study examined effects of bacterial rhamnolipids (RLS) on lipid metabolism, immune response, and gut microbiota in rats. Methods… read more here.
Keywords: nco group; rls2; metabolism immune; lipid metabolism ... See more keywords
Quantitative Serum NMR Spectroscopy Stratifies COVID-19 Patients and Sheds Light on Interfaces of Host Metabolism and the Immune Response with Cytokines and Clinical Parameters
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DOI: 10.3390/metabo12121277
Abstract: The complex manifestations of COVID-19 are still not fully decoded on the molecular level. We combined quantitative the nuclear magnetic resonance (NMR) spectroscopy serum analysis of metabolites, lipoproteins and inflammation markers with clinical parameters and… read more here.
Keywords: metabolism; metabolism immune; spectroscopy; clinical parameters ... See more keywords