Structural and Mechanistic Investigation of the Unusual Metabolism of Nifurtimox
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DOI: 10.1021/acs.chemrestox.2c00210
Abstract: The oral antiparasitic drug nifurtimox has been used to treat Chagas disease for more than 50 years. Historical studies determined that very little nifurtimox is excreted unchanged, but contemporaneous preclinical studies of radiolabeled nifurtimox found… read more here.
Keywords: metabolism nifurtimox; metabolism; structural mechanistic; mechanistic investigation ... See more keywords