Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches
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DOI: 10.1038/onc.2016.485
Abstract: Epigenetic and metabolic alterations in cancer cells are highly intertwined. Oncogene-driven metabolic rewiring modifies the epigenetic landscape via modulating the activities of DNA and histone modification enzymes at the metabolite level. Conversely, epigenetic mechanisms regulate… read more here.
Keywords: epigenetics metabolism; oncogenesis mechanisms; mechanisms therapeutic; metabolism ... See more keywords