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Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.07.026
Abstract: Schizophrenia is a chronic psychiatric disorderwith a heterogeneous studied the effects of betaine supplementation in inbred B6N and genetic and neurobiological background that impacts early brain development and is expressed as a combination of psychotic…
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Keywords:
medicine;
schizophrenia;
metabolism pathway;
first episode ... See more keywords
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Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.05.201
Abstract: Low temperatures retard postharvest ripening and prolong the supply period of 'Nanguo' pears. However, quality deterioration, or more specifically, a faded aroma occurs in long-term cold-stored fruits. To understand the implicit mechanism, we analyzed the…
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Keywords:
metabolism pathway;
cold stored;
fruit;
fatty acid ... See more keywords
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Published in 2022 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s328612
Abstract: Objective The aim of this study is to assess the relationship between the single-nucleotide polymorphism (SNP) in the one-carbon metabolism pathway (MTR rs1805087; MTHFR rs1801133; ALDH1L1 rs2002287, rs2276731; DNMT1 rs16999593, rs2228611; DNMT3B rs2424908) and the…
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Keywords:
risk female;
metabolism pathway;
population;
risk ... See more keywords
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Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.646362
Abstract: Immune checkpoint inhibitors (ICIs) significantly improve the survival of patients with non-small-cell lung cancer (NSCLC), but only some patients obtain clinical benefits. Predictive biomarkers for ICIs can accurately identify people who will benefit from immunotherapy.…
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Keywords:
metabolism pathway;
metabolism;
non small;
cancer ... See more keywords
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Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.902553
Abstract: Background: The incidence of gallstones in the Tibetan population is increasing rapidly. Previous studies indicated that genetic variation located in the cholesterol metabolism pathway may be associated with the incidence of gallstones. Methods: By recruiting…
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Keywords:
metabolism pathway;
cholesterol metabolism;
population;
tibetan population ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.937476
Abstract: Aim Vitamin D (VitD) signaling has been increasingly investigated for its role in stimulating the innate and adaptive immune systems and suppressing inflammatory responses. Therefore, we examined the associations between VitD-related genetic polymorphisms, plasma 25-hydroxyvitamin…
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Keywords:
efficacy safety;
ici treatment;
treatment;
metabolism pathway ... See more keywords
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Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1139775
Abstract: Keloid is a pathological scar formed by abnormal wound healing, characterized by the persistence of local inflammation and excessive collagen deposition, where the intensity of inflammation is positively correlated with the size of the scar…
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Keywords:
metabolism pathway;
metabolism;
analysis;
gsl metabolism ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1019486
Abstract: Schisantherin A (STA) is a traditional Chinese medicine extracted from the plant Schisandra chinensis, which has a wide range of anti-inflammatory, antioxidant, and other pharmacological effects. This study investigates the anti-hepatocellular carcinoma effects of STA…
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Keywords:
metabolism pathway;
metabolism;
hepatocellular carcinoma;
cell proliferation ... See more keywords
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Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.00236
Abstract: Background: The modulation of arachidonic acid (AA) metabolism pathway is identified in metabolic alterations after hypoxia exposure, but its biological function is controversial. We aimed at integrating plasma metabolomic and transcriptomic approaches to systematically explore…
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Keywords:
metabolism pathway;
acid metabolism;
metabolism;
hypoxia exposure ... See more keywords