Articles with "metabolism pathway" as a keyword



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Translational research identifies a metabolism pathway involved in first-episode of schizophrenia: Towards precision medicine

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Published in 2019 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2019.07.026

Abstract: Schizophrenia is a chronic psychiatric disorderwith a heterogeneous studied the effects of betaine supplementation in inbred B6N and genetic and neurobiological background that impacts early brain development and is expressed as a combination of psychotic… read more here.

Keywords: medicine; schizophrenia; metabolism pathway; first episode ... See more keywords
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Low-temperature stress-induced aroma loss by regulating fatty acid metabolism pathway in 'Nanguo' pear.

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Published in 2019 at "Food chemistry"

DOI: 10.1016/j.foodchem.2019.05.201

Abstract: Low temperatures retard postharvest ripening and prolong the supply period of 'Nanguo' pears. However, quality deterioration, or more specifically, a faded aroma occurs in long-term cold-stored fruits. To understand the implicit mechanism, we analyzed the… read more here.

Keywords: metabolism pathway; cold stored; fruit; fatty acid ... See more keywords
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Association Between SNPs in the One-Carbon Metabolism Pathway and the Risk of Female Breast Cancer in a Chinese Population

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Published in 2022 at "Pharmacogenomics and Personalized Medicine"

DOI: 10.2147/pgpm.s328612

Abstract: Objective The aim of this study is to assess the relationship between the single-nucleotide polymorphism (SNP) in the one-carbon metabolism pathway (MTR rs1805087; MTHFR rs1801133; ALDH1L1 rs2002287, rs2276731; DNMT1 rs16999593, rs2228611; DNMT3B rs2424908) and the… read more here.

Keywords: risk female; metabolism pathway; population; risk ... See more keywords
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Prognosis of Non-small-cell Lung Cancer Patients With Lipid Metabolism Pathway Alternations to Immunotherapy

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Published in 2021 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2021.646362

Abstract: Immune checkpoint inhibitors (ICIs) significantly improve the survival of patients with non-small-cell lung cancer (NSCLC), but only some patients obtain clinical benefits. Predictive biomarkers for ICIs can accurately identify people who will benefit from immunotherapy.… read more here.

Keywords: metabolism pathway; metabolism; non small; cancer ... See more keywords
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Association Study Between Polymorphic Loci in Cholesterol Metabolism Pathway and Gallstone in the Tibetan Population

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.902553

Abstract: Background: The incidence of gallstones in the Tibetan population is increasing rapidly. Previous studies indicated that genetic variation located in the cholesterol metabolism pathway may be associated with the incidence of gallstones. Methods: By recruiting… read more here.

Keywords: metabolism pathway; cholesterol metabolism; population; tibetan population ... See more keywords
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Vitamin D metabolism pathway polymorphisms are associated with efficacy and safety in patients under anti-PD-1 inhibitor therapy

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.937476

Abstract: Aim Vitamin D (VitD) signaling has been increasingly investigated for its role in stimulating the innate and adaptive immune systems and suppressing inflammatory responses. Therefore, we examined the associations between VitD-related genetic polymorphisms, plasma 25-hydroxyvitamin… read more here.

Keywords: efficacy safety; ici treatment; treatment; metabolism pathway ... See more keywords
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Revealing the roles of glycosphingolipid metabolism pathway in the development of keloid: a conjoint analysis of single-cell and machine learning

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1139775

Abstract: Keloid is a pathological scar formed by abnormal wound healing, characterized by the persistence of local inflammation and excessive collagen deposition, where the intensity of inflammation is positively correlated with the size of the scar… read more here.

Keywords: metabolism pathway; metabolism; analysis; gsl metabolism ... See more keywords
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Schisantherin A inhibits cell proliferation by regulating glucose metabolism pathway in hepatocellular carcinoma

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.1019486

Abstract: Schisantherin A (STA) is a traditional Chinese medicine extracted from the plant Schisandra chinensis, which has a wide range of anti-inflammatory, antioxidant, and other pharmacological effects. This study investigates the anti-hepatocellular carcinoma effects of STA… read more here.

Keywords: metabolism pathway; metabolism; hepatocellular carcinoma; cell proliferation ... See more keywords

Arachidonic Acid Metabolism Pathway Is Not Only Dominant in Metabolic Modulation but Associated With Phenotypic Variation After Acute Hypoxia Exposure

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Published in 2018 at "Frontiers in Physiology"

DOI: 10.3389/fphys.2018.00236

Abstract: Background: The modulation of arachidonic acid (AA) metabolism pathway is identified in metabolic alterations after hypoxia exposure, but its biological function is controversial. We aimed at integrating plasma metabolomic and transcriptomic approaches to systematically explore… read more here.

Keywords: metabolism pathway; acid metabolism; metabolism; hypoxia exposure ... See more keywords