Succinylation Links Metabolism to Protein Functions
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DOI: 10.1007/s11064-019-02780-x
Abstract: Post-translational modifications (PTMs) are important regulators of protein function, and integrate metabolism with physiological and pathological processes. Phosphorylation and acetylation are particularly well studied PTMs. A relatively recently discovered novel PTM is succinylation in which… read more here.
Keywords: metabolism protein; succinylation; metabolism; succinylation links ... See more keywords
DynamicME: dynamic simulation and refinement of integrated models of metabolism and protein expression
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DOI: 10.1186/s12918-018-0675-6
Abstract: Genome-scale models of metabolism and macromolecular expression (ME models) enable systems-level computation of proteome allocation coupled to metabolic phenotype. We develop dynamicME, an algorithm enabling time-course simulation of cell metabolism and protein expression. Our dynamicME… read more here.
Keywords: protein expression; metabolism protein; models metabolism; metabolism ... See more keywords